Detalhe da pesquisa
1.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Cell
; 187(10): 2536-2556.e30, 2024 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38653237
2.
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway.
Cell
; 186(11): 2361-2379.e25, 2023 05 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37192619
3.
An Electrochemical Approach to Directed Fluorination.
J Org Chem
; 88(4): 2557-2560, 2023 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36702475
4.
Spectroscopic and Crystallographic Characterization of the R3 N+ -C-Hâ â â X Interaction.
Chemistry
; 28(8): e202103922, 2022 Feb 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35133051
5.
Rational Computational Design of Systems Exhibiting Strong Halogen Bonding Involving Fluorine in Bicyclic Diamine Derivatives.
J Org Chem
; 87(13): 8413-8419, 2022 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35658438
6.
C-F Bonds as "Frozen" Nucleophiles: Unconsummated SN2 Reactions.
J Org Chem
; 87(19): 13406-13410, 2022 10 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36166828
7.
The Close Interaction of a C-F Bond with an Amide Carbonyl: Crystallographic and Spectroscopic Characterization.
Angew Chem Int Ed Engl
; 61(34): e202207966, 2022 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35716396
8.
Carbonyl-Directed Aliphatic Fluorination: A Special Type of Hydrogen Atom Transfer Beats Out Norrish II.
J Am Chem Soc
; 142(34): 14710-14724, 2020 08 26.
Artigo
Inglês
| MEDLINE | ID: mdl-32786786
9.
Sensitized Aliphatic Fluorination Directed by Terpenoidal Enones: A "Visible Light" Approach.
J Org Chem
; 83(3): 1565-1575, 2018 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29293338
10.
Catalyzed and Promoted Aliphatic Fluorination.
J Org Chem
; 83(16): 8803-8814, 2018 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29894188
11.
Multiple Enone-Directed Reactivity Modes Lead to the Selective Photochemical Fluorination of Polycyclic Terpenoid Derivatives.
J Am Chem Soc
; 139(6): 2208-2211, 2017 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28146358
12.
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.
bioRxiv
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38798357
13.
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
bioRxiv
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38798619
14.
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
Cell Metab
; 35(3): 487-503.e7, 2023 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36841242
15.
Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway.
bioRxiv
; 2023 Mar 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36945474
16.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
bioRxiv
; 2023 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37961514
17.
Hydroxy-directed fluorination of remote unactivated C(sp3)-H bonds: a new age of diastereoselective radical fluorination.
Chem Sci
; 13(23): 7007-7013, 2022 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35774162
18.
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer.
Cell Metab
; 35(4): 722, 2023 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37019082
19.
Ketones as directing groups in photocatalytic sp3 C-H fluorination.
Chem Sci
; 8(10): 6918-6923, 2017 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29147517