Detalhe da pesquisa
1.
BacPROTACs mediate targeted protein degradation in bacteria.
Cell
; 185(13): 2338-2353.e18, 2022 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-35662409
2.
Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex.
Cell
; 172(3): 454-464.e11, 2018 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29361316
3.
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell
; 170(4): 701-713.e11, 2017 Aug 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28781166
4.
Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell
; 165(6): 1440-1453, 2016 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27259151
5.
A molecular network of conserved factors keeps ribosomes dormant in the egg.
Nature
; 613(7945): 712-720, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36653451
6.
Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5.
EMBO J
; 42(16): e113348, 2023 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37409633
7.
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature
; 599(7885): 491-496, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34711951
8.
Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol Cell
; 63(4): 593-607, 2016 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-27522463
9.
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat Chem Biol
; 17(10): 1084-1092, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34294896
10.
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc Natl Acad Sci U S A
; 116(35): 17280-17289, 2019 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31350353
11.
Mechanism of APC/CCDC20 activation by mitotic phosphorylation.
Proc Natl Acad Sci U S A
; 113(19): E2570-8, 2016 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27114510
12.
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space.
Nat Methods
; 12(9): 859-65, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26237227
13.
Structural basis for cooperativity of CRM1 export complex formation.
Proc Natl Acad Sci U S A
; 110(3): 960-5, 2013 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23277578
14.
Frozen in time: analyzing molecular dynamics with time-resolved cryo-EM.
Structure
; 31(1): 4-19, 2023 01 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36584678
15.
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat Struct Mol Biol
; 30(11): 1663-1674, 2023 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-37735619
16.
Structure of the peripheral arm of a minimalistic respiratory complex I.
Structure
; 30(1): 80-94.e4, 2022 01 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34562374
17.
Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1.
Nat Struct Mol Biol
; 29(9): 942-953, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36097293
18.
Cryo-EM structure of the plant 26S proteasome.
Plant Commun
; 3(3): 100310, 2022 05 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35576154
19.
Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.
Science
; 378(6615): eabn5637, 2022 10 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36074822
20.
Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.
Nat Commun
; 12(1): 3483, 2021 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34108481