Detalhe da pesquisa
1.
Discovery of a Potent and Orally Bioavailable Zwitterionic Series of Selective Estrogen Receptor Degrader-Antagonists.
J Med Chem
; 66(4): 2918-2945, 2023 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36727211
2.
Photoredox Catalysis: 1,4-Conjugate Addition of N-Methyl Radicals to Electron-Deficient Olefins via Decarboxylation of N-Substituted Acetic Acids.
Org Lett
; 22(9): 3418-3422, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32311269
3.
Addition of Fluorine and a Late-Stage Functionalization (LSF) of the Oral SERD AZD9833.
ACS Med Chem Lett
; 11(12): 2519-2525, 2020 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33335676
4.
Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist.
J Med Chem
; 63(23): 14530-14559, 2020 12 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32910656
5.
Discovery of efficacious Pseudomonas aeruginosa-targeted siderophore-conjugated monocarbams by application of a semi-mechanistic pharmacokinetic/pharmacodynamic model.
J Med Chem
; 58(5): 2195-205, 2015 Mar 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25658376
6.
A novel estrogen receptor ligand template.
Bioorg Med Chem Lett
; 13(11): 1919-22, 2003 Jun 02.
Artigo
Inglês
| MEDLINE | ID: mdl-12749898
7.
Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor.
Bioorg Med Chem Lett
; 12(12): 1559-62, 2002 Jun 17.
Artigo
Inglês
| MEDLINE | ID: mdl-12039561