Detalhe da pesquisa
1.
Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell
; 175(7): 1856-1871.e21, 2018 12 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30503205
2.
A systematic analysis of regression models for protein engineering.
PLoS Comput Biol
; 20(5): e1012061, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38701099
3.
Single-particle diffusional fingerprinting: A machine-learning framework for quantitative analysis of heterogeneous diffusion.
Proc Natl Acad Sci U S A
; 118(31)2021 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34321355
4.
Carbohydrate-Derived Metal-Chelator-Triggered Lipids for Liposomal Drug Delivery.
Chemistry
; 27(23): 6917-6922, 2021 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-33411939
5.
Label-Free Fluorescence Quantification of Hydrolytic Enzyme Activity on Native Substrates Reveals How Lipase Function Depends on Membrane Curvature.
Langmuir
; 36(23): 6473-6481, 2020 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32437165
6.
Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells.
Nat Chem Biol
; 13(7): 724-729, 2017 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-28481347
7.
Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment.
Biophys J
; 113(6): 1269-1279, 2017 Sep 19.
Artigo
Inglês
| MEDLINE | ID: mdl-28738989
8.
Effects of membrane curvature and pH on proton pumping activity of single cytochrome bo3 enzymes.
Biochim Biophys Acta Bioenerg
; 1858(9): 763-770, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28634030
9.
Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases.
Nat Chem Biol
; 11(3): 192-4, 2015 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-25622090
10.
Single Enzyme Experiments Reveal a Long-Lifetime Proton Leak State in a Heme-Copper Oxidase.
J Am Chem Soc
; 137(51): 16055-63, 2015 Dec 30.
Artigo
Inglês
| MEDLINE | ID: mdl-26618221
11.
Shedding light on protein folding, structural and functional dynamics by single molecule studies.
Molecules
; 19(12): 19407-34, 2014 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-25429564
12.
Everything, everywhere, almost at once.
Elife
; 132024 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38285015
13.
Constitutive Endolysosomal Perforation in Neurons allows Induction of α-Synuclein Aggregation by Internalized Pre-Formed Fibrils.
bioRxiv
; 2024 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38260258
14.
SEMORE: SEgmentation and MORphological fingErprinting by machine learning automates super-resolution data analysis.
Nat Commun
; 15(1): 1763, 2024 Feb 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38409214
15.
Deconvoluting the Effect of Cell-Penetrating Peptides for Enhanced and Controlled Insertion of Large-Scale DNA Nanopores.
ACS Appl Mater Interfaces
; 16(15): 18422-18433, 2024 Apr 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38573069
16.
Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation.
Sci Rep
; 14(1): 7665, 2024 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38561398
17.
Monitoring shifts in the conformation equilibrium of the membrane protein cytochrome P450 reductase (POR) in nanodiscs.
J Biol Chem
; 287(41): 34596-603, 2012 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-22891242
18.
In vitro and in vivo immunogenicity assessment of protein aggregate characteristics.
Int J Pharm
; 631: 122490, 2023 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36521637
19.
Single-Particle Tracking of Thermomyces lanuginosus Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion.
Biomolecules
; 13(4)2023 03 31.
Artigo
Inglês
| MEDLINE | ID: mdl-37189378
20.
Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy.
J Phys Chem Lett
; 14(4): 912-919, 2023 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36669144