Detalhe da pesquisa
1.
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.
Hum Mol Genet
; 27(18): 3257-3271, 2018 09 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29917075
2.
Dopamine: Functions, Signaling, and Association with Neurological Diseases.
Cell Mol Neurobiol
; 39(1): 31-59, 2019 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-30446950
3.
Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2.
Neurochem Res
; 44(6): 1446-1459, 2019 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-30291536
4.
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Proc Natl Acad Sci U S A
; 111(7): 2626-31, 2014 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24510904
5.
Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution.
J Biol Chem
; 289(31): 21386-400, 2014 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24942733
6.
Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers.
J Neurochem
; 130(6): 839-53, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24832775
7.
Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism.
Neurobiol Dis
; 51: 35-42, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23064436
8.
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation.
Biochem J
; 446(1): 99-111, 2012 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22612223
9.
Longitudinal Characterization of Transcriptomic, Functional, and Morphological Features in Human iPSC-Derived Neurons and Their Application to Investigate Translational Progranulin Disease Biology.
Front Aging Neurosci
; 12: 576678, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33281596
10.
The Effects of Variants in the Parkin, PINK1, and DJ-1 Genes along with Evidence for their Pathogenicity.
Curr Protein Pept Sci
; 18(7): 702-714, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-26965687
11.
Hexokinases link DJ-1 to the PINK1/parkin pathway.
Mol Neurodegener
; 12(1): 70, 2017 09 29.
Artigo
Inglês
| MEDLINE | ID: mdl-28962651
12.
Astrocytes in Parkinson's disease and DJ-1.
J Neurochem
; 117(3): 357-8, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21413989
13.
The Polg Mutator Phenotype Does Not Cause Dopaminergic Neurodegeneration in DJ-1-Deficient Mice.
eNeuro
; 2(1)2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26464968
14.
Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain.
PLoS One
; 9(4): e94646, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24722488
15.
Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4.
Free Radic Biol Med
; 65: 419-427, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-23816523
16.
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex.
Nat Neurosci
; 16(4): 499-506, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23416452
17.
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both.
Autophagy
; 6(8): 1090-106, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20890124