Detalhe da pesquisa
1.
Swedish Alzheimer's disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways.
J Biol Chem
; 300(4): 107137, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38447793
2.
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Neurobiol Dis
; 179: 106050, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36809847
3.
Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau.
Alzheimers Dement
; 19(10): 4662-4674, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37002928
4.
Development of GMP-1 a molecular chaperone network modulator protecting mitochondrial function and its assessment in fly and mice models of Alzheimer's disease.
J Cell Mol Med
; 22(7): 3464-3474, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29704317
5.
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form.
Neurobiol Dis
; 106: 191-204, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-28711409
6.
Late-stage α-synuclein accumulation in TNWT-61 mouse model of Parkinson's disease detected by diffusion kurtosis imaging.
J Neurochem
; 136(6): 1259-1269, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26685006
7.
Influence of Lentiviral ß-Synuclein Overexpression in the Hippocampus of a Transgenic Mouse Model of Alzheimer's Disease on Amyloid Precursor Protein Metabolism and Pathology.
Neurodegener Dis
; 15(4): 243-57, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26111745
8.
Neuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease.
J Neuroinflammation
; 11: 84, 2014 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24886182
9.
Amyloid precursor protein induces reactive astrogliosis.
Acta Physiol (Oxf)
; 240(6): e14142, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38584589
10.
Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model.
BMC Neurosci
; 14: 6, 2013 Jan 09.
Artigo
Inglês
| MEDLINE | ID: mdl-23302418
11.
Amyloid precursor protein induces reactive astrogliosis.
bioRxiv
; 2023 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38187544
12.
MRI in dementia.
Neurol Clin
; 27(1): 221-36, ix, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19055981
13.
BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
PLoS One
; 13(7): e0200344, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29979789
14.
Diffusion Kurtosis Imaging Detects Microstructural Alterations in Brain of α-Synuclein Overexpressing Transgenic Mouse Model of Parkinson's Disease: A Pilot Study.
Neurotox Res
; 28(4): 281-9, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26153486
15.
Increased efflux of amyloid-ß peptides through the blood-brain barrier by muscarinic acetylcholine receptor inhibition reduces pathological phenotypes in mouse models of brain amyloidosis.
J Alzheimers Dis
; 38(4): 767-86, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24072071
16.
Tracking of magnetite labeled nanoparticles in the rat brain using MRI.
PLoS One
; 9(3): e92068, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24633006
17.
Impact of ApoB-100 expression on cognition and brain pathology in wild-type and hAPPsl mice.
Neurobiol Aging
; 34(10): 2379-88, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23643485
18.
In vivo and ex vivo imaging of amyloid-ß cascade aggregates with a Pronucleon™ peptide.
J Alzheimers Dis
; 34(4): 957-67, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23321523
19.
Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice.
Mol Neurodegener
; 7: 61, 2012 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23249765
20.
A longitudinal study of behavioral deficits in an AßPP transgenic mouse model of Alzheimer's disease.
J Alzheimers Dis
; 25(2): 231-43, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21403389