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1.
Eur J Nutr ; 62(8): 3329-3338, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37592132

RESUMO

PURPOSE: Populations following a plant-based diet may be at particular risk of thyroid dysfunction due to low iodine and selenium intakes. The main purpose was to assess thyroid function and urinary concentration of iodine, selenium, and arsenic, in subjects following a vegan, lacto-ovo vegetarian, or pescatarian diet. METHODS: In Norway, a country without mandatory dietary iodine fortification, 205 adults, following vegan (n = 115), lacto-ovo vegetarian (n = 55) and pescatarian diet (n = 35) were included. Thyroglobulin (Tg), thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), and serum anti-TPO (S-anti-TPO) were measured in a venous blood sample and concentrations of iodine (UIC), creatinine (UCC), selenium, and arsenic were measured from single spot urine samples. RESULTS: Subclinical hypothyroidism (TSH > 4.0 mU/L) was observed in 3% of subjects. The overall median (p25, p75) Tg was 17 (9, 30) µg/L and vegans had higher Tg compared to pescatarians. Vegans not consuming iodine-containing supplements (n = 43) had higher Tg, than supplement users (n = 72), 27 (11, 44) vs. 16 (8, 25) µg/L and higher fT4, 16 (15, 17) vs. 15 (14, 17) pmol/L, respectively. The overall median UIC was 57 (28, 130) µg/L, all dietary groups had median UIC below WHO thresholds. Median urinary selenium and arsenic concentration was 13 (6, 22) and 3 (2, 8) µg/L, respectively. CONCLUSION: The prevalence of subclinical hypothyroidism was low and fT4 and fT3 were within the normal range for all dietary groups. Vegans had significantly increased Tg compared to pescatarians.


Assuntos
Arsênio , Hipotireoidismo , Iodo , Selênio , Adulto , Humanos , Iodo/urina , Veganos , Hipotireoidismo/epidemiologia , Tireotropina , Tiroxina , Vegetarianos
2.
Br J Nutr ; : 1-8, 2022 Sep 27.
Artigo em Inglês | MEDLINE | ID: mdl-36165126

RESUMO

Plant-based diets may increase the risk of vitamin B12 deficiency due to limited intake of animal-source foods, while dietary folate increases when adhering to plant-based diets. In this cross-sectional study, we evaluated the B12 and folate status of Norwegian vegans and vegetarians using dietary B12 intake, B12 and folic acid supplement use, and biomarkers (serum B12 (B12), plasma total homocysteine (tHcy), plasma methylmalonic acid (MMA) and serum folate). Vegans (n 115) and vegetarians (n 90) completed a 24-h dietary recall and a FFQ and provided a non-fasting blood sample. cB12, a combined indicator for evaluation of B12 status, was calculated. B12 status was adequate in both vegans and vegetarians according to the cB12 indicator; however 4 % had elevated B12. Serum B12, tHcy, MMA concentrations and the cB12 indicator (overall median: 357 pmol/l, 9·0 µmol/l, 0·18 µmol/l, 1·30 (cB12)) did not differ between vegans and vegetarians, unlike for folate (vegans: 25·8 nmol/l, vegetarians: 21·6 nmol/l, P = 0·027). Serum B12 concentration < 221 pmol/l was found in 14 % of all participants. Vegetarians revealed the highest proportion of participants below the recommended daily intake of 2 µg/d including supplements (40 v. 18 %, P < 0·001). Predictors of higher serum B12 concentrations were average daily supplement use and older age. Folate deficiency (< 10 nmol/l) was uncommon overall (< 2·5 %). The combined indicator cB12 suggested that none of the participants was B12-depleted; however, low serum B12 concentration was found in 14 % of the participants. Folate concentrations were adequate, indicating adequate folate intake in Norwegian vegans and vegetarians.

3.
BMC Public Health ; 22(1): 720, 2022 04 11.
Artigo em Inglês | MEDLINE | ID: mdl-35410198

RESUMO

AIMS: To prevent type 2 diabetes mellitus (T2D) and reduce the risk of complications, early identification of people at risk of developing T2D, preferably through simple diabetes risk scores, is essential. The aim of this study was to create a risk score for identifying subjects with undiagnosed prediabetes or T2D among Saharawi refugees in Algeria and compare the performance of this score to the Finnish diabetes risk score (FINDRISC). METHODS: A cross-sectional survey was carried out in five Saharawi refugee camps in Algeria in 2014. A total of 180 women and 175 men were included. HbA1c and cut-offs proposed by the American Diabetes Association (ADA) were used to define cases. Variables to include in the risk score were determined by backwards elimination in logistic regression. Simplified scores were created based on beta coefficients from the multivariable model after internal validation with bootstrapping and shrinkage. The empirical cut-off value for the simplified score and FINDRISC was determined by Area Under the Receiver Operating Curve (AUROC) analysis. RESULTS: Variables included in the final risk score were age, body mass index (BMI), and waist circumference. The area under the curve (AUC) (C.I) was 0.82 (0.76, 0.88). The sensitivity, specificity, and positive and negative predictive values were 89, 65, 28, and 97%, respectively. AUC and sensitivity were slightly higher and specificity somewhat lower than for FINDRISC. CONCLUSIONS: The risk score developed is a helpful tool to decide who should be screened for prediabetes or T2D by blood sample analysis. The performance of the risk score was adequate based on internal validation with bootstrap analyses, but should be confirmed in external validation studies.


Assuntos
Diabetes Mellitus Tipo 2 , Estado Pré-Diabético , Refugiados , Argélia/epidemiologia , Estudos Transversais , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/epidemiologia , Feminino , Humanos , Masculino , Estado Pré-Diabético/diagnóstico , Estado Pré-Diabético/epidemiologia , Fatores de Risco
4.
Compr Rev Food Sci Food Saf ; 21(2): 1517-1536, 2022 03.
Artigo em Inglês | MEDLINE | ID: mdl-35233943

RESUMO

Brown algae are becoming increasingly popular as a food source and dietary supplement in Europe and other Western countries. As they are highly rich in iodine, they represent a potential new dietary iodine source. Iodine deficiency has been re-emerging in Europe, and it is important to ensure adequate intake through one's diet. However, macroalgae, and especially brown algae, may contain very high amounts of iodine, and both iodine deficiency and excessive iodine may increase the risk of negative health effects. The iodine content of algae or foods containing algae is currently not regulated in the European Union. The aim of this paper is to review the literature to determine the chemical species of iodine in brown algae, the loss of iodine during processing, and the bioavailability and bioaccessibility of iodine. A systematic search of the literature was performed in April 2021, via the databases Web of Science and PubMed. The review includes studies of iodine in brown macroalgae in relation to bioavailability, bioaccessibility, processing and speciation. A meta-analysis was conducted in relation to the following topics: (i) the correlation between total iodine and iodide (I- ) content in brown algae; (ii) the correlation between the loss of iodine during processing and the I- content; and (iii) the correlation between bioavailability and the I- content. The bioavailability of iodine from brown algae was generally high, with in vivo bioavailability ranging from 31% to 90%. The in vitro bioavailability of iodine (2%-28%) was systematically lower than in vivo bioavailability (31%-90%), indicating an inadequate in vitro methodology. Processing may reduce the iodine content of brown algae, and a higher I- content was positively correlated with increased iodine loss during processing. Although processing strategies may reduce the iodine content of brown algae significantly, the iodine content may still be high after processing. These findings may be used in food safety evaluations of brown algae as well as in the development of macroalgae-containing foods with iodine contents suitable for human consumption. Further research on processing techniques to reduce the iodine content in brown macroalgae are warranted.


Assuntos
Iodo , Phaeophyceae , Alga Marinha , Disponibilidade Biológica , Humanos , Iodetos , Iodo/análise , Alga Marinha/química
5.
BMC Public Health ; 21(1): 166, 2021 01 19.
Artigo em Inglês | MEDLINE | ID: mdl-33468100

RESUMO

BACKGROUND: The Sahrawi people fled their homes in 1975 as the conflict in Western Sahara escalated and settled down near Tindouf, Algeria, where they still live. High prevalence of overweight and obesity and type 2 diabetes had been found in this protracted refugee setting. Scaling up national policy efforts to promote physical activity (PA) is critical to reducing the prevalence of noncommunicable diseases (NCDs) in the near future. One possible barrier to the inclusion of PA in NCD prevention strategies is the lack of research on PA level, which may reduce political support and policy development for PA. Thus, the aim of this study was to investigate the PA level among adults living in Sahrawi refugee camps and socioeconomic factors associated with PA. METHODS: A cross-sectional survey was carried out in 2014 in five refugee camps near Tindouf, Algeria. A total of 180 women and 175 men were included. PA was measured using the international physical activity questionnaire short form (IPAQ-SF). RESULTS: There was a large amount of variance in reported PA for both genders, ranging from 10 min of total PA per week to above 40 h. Forty-three percent of the participants had a low PA level (defined as not meeting the PA recommendations of 150 min of moderate to vigorous PA per day). The chi-square test of independence showed that males, those aged ≥ 60 years and people with higher education were more likely to be in the low PA level category. No significant relationship was found between PA level and BMI status. Most of the participants thought that engaging in PA would be wise, valuable, right and good but thought to a lesser degree that PA would be easy, comfortable and interesting. CONCLUSIONS: Almost half of the participants were categorised as insufficiently physically active, however, most of the Sahrawi refugees express a positive attitude towards PA. PA is a low-cost approach to reducing deaths and NCDs, government initiatives to increase PA levels in refugee camps are advised.


Assuntos
Diabetes Mellitus Tipo 2 , Refugiados , Adulto , África , Idoso , Argélia/epidemiologia , Estudos Transversais , Exercício Físico , Feminino , Humanos , Masculino , Inquéritos e Questionários
6.
Matern Child Nutr ; 17(1): e13050, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32602197

RESUMO

Iodine deficiency during pregnancy and in the post-partum period may lead to impaired child development. Our aim is to describe iodine status longitudinally in women from pregnancy until 18 months post-partum. Furthermore, we explore whether iodine status is associated with dietary intake, iodine-containing supplement use and breastfeeding status from pregnancy until 18 months post-partum. We also assess the correlation between maternal iodine status 18 months post-partum and child iodine status at 18 months of age. Iodine status was measured by urinary iodine concentration (UIC) during pregnancy (n = 1,004), 6 weeks post-partum (n = 915), 6 months post-partum (n = 849), 12 months post-partum (n = 733) and 18 months post-partum (n = 714). The toddlers' UIC was assessed at 18 months of age (n = 416). Demographic variables and dietary data (food frequency questionnaire) were collected during pregnancy, and dietary data and breastfeeding practices were collected at all time points post-partum. We found that iodine status was insufficient in both pregnant and post-partum women. The UIC was at its lowermost 6 weeks post-partum and gradually improved with increasing time post-partum. Intake of milk and use of iodine-containing supplements significantly increased the odds of having a UIC above 100 µg/L. Neither the mothers' UIC, vegetarian practice, nor exclusion of milk and dairy products were associated with the toddlers UIC 18 months post-partum. Women who exclude milk and dairy products from their diets and/or do not use iodine-containing supplements may be at risk of iodine deficiency. The women possibly also have an increased risk of thyroid dysfunction and for conceiving children with nonoptimal developmental status.


Assuntos
Iodo , Animais , Aleitamento Materno , Feminino , Humanos , Leite/química , Estado Nutricional , Período Pós-Parto , Gravidez
7.
BMC Pediatr ; 20(1): 279, 2020 06 05.
Artigo em Inglês | MEDLINE | ID: mdl-32503470

RESUMO

BACKGROUND: Existing literature shows that there is an inverse association between socioeconomic position and screen time among adolescents. What is less known is the mechanism behind these differences. The study aimed to explore individual, interpersonal and neighborhood environmental correlates of total screen time (TST) among adolescents and to assess their mediating role in the association between parental education and TST. METHODS: A cross-sectional study including 706 adolescents (mean age of 13.6 (SD = 0.3)) was used to collect data at schools through an online questionnaire. Multiple regression analyses were used to explore factors associated with TST. Mediation analyses were conducted to assess whether these factors mediated the association between parental education and TST. RESULTS: Multiple linear regression analyses, adjusted for gender and age, showed that parental modelling of TV and movie streaming, TV/movie streaming during dinner and access to screens were positively related to TST. Self-efficacy towards limiting TV and movie streaming, self-efficacy towards limiting computer/electronic game use, and the perceived opportunities for physical activity in the neighborhood were inversely related to total screen time. All of these factors except self-efficacy towards limiting TV and movie streaming mediated the association between parental education and TST. CONCLUSIONS: The study identified several modifiable factors at the individual, interpersonal and neighborhood environmental levels that can be targeted in interventions aimed at decreasing screen time among youth in general and among those with a low socioeconomic position in particular.


Assuntos
Tempo de Tela , Comportamento Sedentário , Adolescente , Estudos Transversais , Humanos , Pais , Televisão
8.
BMC Health Serv Res ; 20(1): 585, 2020 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-32590999

RESUMO

BACKGROUND: The World Health Organization (WHO) recommends early essential newborn care (EENC) - The First Embrace - as a simple lifesaving procedure for newborns. The successful implementation of EENC at scale requires an understanding of health staff experiences, including facilitators, barriers, and local adaptations of EENC. This study aims to gain insight into health staff experiences with implementation of EENC guidelines after participation in training and coaching initiatives in Da Nang municipality and Quang Nam province in Viet Nam. METHODS: In each province/municipality, we randomly selected one hospital from the following categories: public provincial/municipal hospital, public district hospital, and private hospital. We conducted in-depth interviews with 19 hospital staff (11 midwives, 5 doctors and 3 health managers) and two trainers during 7 days between September and October 2017. We used deductive/inductive thematic analysis to generate themes. RESULTS: The health staff reported improved staff and mother satisfaction, and health benefits for both mothers and newborns after implementing EENC. Facilitators to successful implementation were management support for resource allocation and collaboration across departments, and creative demand generation. Barriers included staff shortage, skepticism about the new protocols and practices and challenges translating knowledge and skills from trainings and coaching into practice. CONCLUSIONS: After implementing EENC, through training and coaching using the WHO approach, health staff reported improved staff and mother satisfaction as well as health benefits for both mothers and newborns. An approach to develop competencies, with a focus on practical training and coaching, should be promoted to form, reinforce and sustain recommended EENC practices among health staff.


Assuntos
Cuidado do Lactente , Recursos Humanos em Hospital , Feminino , Hospitais de Distrito , Humanos , Recém-Nascido , Masculino , Tocologia , Mães , Guias de Prática Clínica como Assunto , Gravidez , Pesquisa Qualitativa , Vietnã , Organização Mundial da Saúde
9.
BMC Public Health ; 19(1): 592, 2019 May 17.
Artigo em Inglês | MEDLINE | ID: mdl-31101092

RESUMO

BACKGROUND: High prevalence of food insecurity has been observed among asylum seekers resettled in high-income countries. Economic constraints, lack of knowledge about new foods, difficulties with shopping, challenges with language, as well as problems complying with various religious food rules are associated with the occurrence and severity of food insecurity. However, no data on food security among asylum seekers in Norway currently exist. Thus, the aim of the study was to assess food security among asylum seekers living in Norwegian reception centers. METHODS: Using convenience sampling, we selected eight reception centers in the southeastern part of Norway and included 205 asylum seekers, including 41 families with children < 18 years of age. We measured food security using the 10-item version of the Radimer/Cornell Hunger and Food Insecurity Scale. Food insecure participants were divided into three groups: food insecurity without hunger, food insecurity with hunger, or food insecurity with child hunger. Using logistic regression models, we analyzed the association between food insecurity status and socioeconomic variables. RESULTS: Seven percent of the participants were categorized as food secure and 93% as food insecure, of whom 11% were food insecure without hunger, 78% were food insecure with hunger, and 4% were food insecure with child hunger. Among the families with children, 20% (8 of 41) experienced child hunger. For the participants experiencing food insecurity with hunger, 44% reported that they were hungry often, and among families with children, 14% reported that despite being aware of the child's hunger, they did not have the resources/money to buy more food. In logistic regression models, men had higher odds of experiencing adult food insecurity with hunger than women, OR (95% CI): 4.08 (2.04, 8.16). A reduction in monthly budget by 100 euros increased the odds of experiencing adult food in-security with hunger by 1.37 times OR (95% CI), 1.37 (1.16, 1.61). CONCLUSIONS: The prevalence of food insecurity among asylum seekers in Norway was high, in contrast to low prevalence of food insecurity in the Norwegian population. Asylum seekers are a particularly vulnerable group and initiatives to ameliorate the opportunities for an adequate diet are of the outmost importance.


Assuntos
Abastecimento de Alimentos/estatística & dados numéricos , Refugiados/estatística & dados numéricos , Adolescente , Adulto , Ansiedade/epidemiologia , Criança , Estudos Transversais , Feminino , Humanos , Fome , Renda , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Noruega/epidemiologia , Prevalência , Refugiados/psicologia , Fatores Sexuais , Fatores Socioeconômicos
10.
Tidsskr Nor Laegeforen ; 139(2)2019 01 29.
Artigo em Norueguês | MEDLINE | ID: mdl-30698392

RESUMO

BACKGROUND: In 2016, the Norwegian National Nutrition Council concluded that inadequate iodine intake is widespread in sections of the Norwegian population, and that effective measures should be undertaken immediately. This literature review aims to summarise articles published since January 2016 that describe the iodine intake in Norway. MATERIAL AND METHOD: Literature searches were conducted in PubMed and Embase. Altogether thirteen articles that reported intake of iodine from the diet or urinary iodine concentration were included. RESULTS: The recent studies confirm that inadequate iodine intake is widespread among women of fertile age, pregnant and breastfeeding women, infants who are exclusively breastfed, elderly persons, vegans and immigrants. There are few sources of iodine in the diet, and persons who avoid or have a low intake of milk and white fish are particularly vulnerable. INTERPRETATION: Inadequate iodine intake is a matter of particular concern in women of fertile age. Healthcare personnel should be aware of this and in certain cases recommend iodine-rich foods or iodine supplements to these and other vulnerable groups.


Assuntos
Iodo , Estado Nutricional , Adolescente , Adulto , Idoso , Aleitamento Materno , Criança , Pré-Escolar , Dieta , Suplementos Nutricionais , Emigrantes e Imigrantes , Feminino , Humanos , Lactente , Iodo/administração & dosagem , Iodo/deficiência , Iodo/uso terapêutico , Iodo/urina , Fenômenos Fisiológicos da Nutrição Materna , Leite Humano/química , Noruega , Gravidez , Complicações na Gravidez , Recomendações Nutricionais , Veganos
11.
Pediatr Res ; 84(4): 509-515, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30030503

RESUMO

BACKGROUND: Nutrient deficiencies limit the growth and turnover of intestinal mucosa, but studies assessing whether specific nutrients protect against or improve environmental enteric dysfunction (EED) are scarce. We aimed to investigate associations between nutrient intake and EED assessed by lactulose:mannitol (L:M) ratio, anti-1-antitrypsin, myeloperoxidase (MPO), and neopterin (NEO) among children 9-24 months in Bhaktapur, Nepal. METHODS: Among 231 included children, nutrient intake was assessed monthly by 24 h recalls, and 3-month usual intake was estimated using Multiple Source Method. Associations between nutrient intake and L:M ratio (measured at 15 months) were assessed using multiple linear regression, while associations between nutrient intake and fecal markers (measured quarterly) were assessed using Generalized Estimating Equations (GEE) models. RESULTS: We found that associations between nutrient intake from complementary food and L:M ratio, alpha-1-antitrypsin (AAT), MPO and NEO were generally negative but weak. The only significant associations between nutrient intake (potassium, magnesium, phosphorous, folate, and vitamin C) and markers for intestinal inflammation were found for MPO. CONCLUSION: Negative but weak associations between nutrient intake and markers of intestinal inflammation were found. Significant associations between several nutrients and MPO might merit further investigation.


Assuntos
Dieta , Enteropatias/epidemiologia , Mucosa Intestinal/patologia , Nutrientes , Biomarcadores/metabolismo , Aleitamento Materno , Ciências da Nutrição Infantil , Pré-Escolar , Estudos de Coortes , Ingestão de Energia , Fezes , Feminino , Humanos , Lactente , Inflamação , Lactulose/metabolismo , Masculino , Manitol/metabolismo , Neopterina/urina , Nepal/epidemiologia , Peroxidase/urina , Análise de Regressão , alfa 1-Antitripsina/urina
12.
Pediatr Res ; 84(5): 611-618, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-29967525

RESUMO

BACKGROUND: Many children worldwide have poor vitamin B12 status. The objective of this study was to estimate association between maternal and infant vitamin B12 status and long-term growth. METHODS: We randomly selected 500 Nepali mother-infant pairs and measured maternal intake and infant and maternal vitamin B12 status using plasma cobalamin, total plasma homocysteine, and methylmalonic acid concentrations. We revisited available children when they were 5 years old and measured growth. The associations between intake and maternal and infant markers of vitamin B12 and growth were estimated in multiple linear regression models adjusting for relevant confounders (n = 331). RESULTS: Maternal vitamin B12 intake and status and vitamin B12 status in infancy predicted linear growth at 5 years of age, but not during infancy. Each microgram increase in the vitamin B12 intake of the mother during infancy was associated with an increase in height of 0.4 (0.2, 0.6) height-for-age z-scores and 1.7 (0.7, 2.7) cm around the child's fifth birthday. CONCLUSION: Vitamin B12 status and intake in early life is an important determinant for linear growth at school age. Our findings should be verified in randomized, placebo controlled trials before translated into public health recommendations.


Assuntos
Crescimento , Vitamina B 12/sangue , Adolescente , Adulto , Aleitamento Materno , Pré-Escolar , Dieta , Feminino , Ácido Fólico/sangue , Homocisteína/sangue , Humanos , Lactente , Lactação , Limite de Detecção , Masculino , Ácido Metilmalônico/sangue , Pessoa de Meia-Idade , Nepal , Distribuição Aleatória , Adulto Jovem
13.
Int J Behav Nutr Phys Act ; 15(1): 61, 2018 06 28.
Artigo em Inglês | MEDLINE | ID: mdl-29954397

RESUMO

BACKGROUND: Over the recent past, there has been an increase in nutrition information available to adolescents from various sources, which resulted into confusion and misinterpretation of the dietary advice. Results from international assessment frameworks such as PISA and TIMMS reflect the need for adolescents to critically appraise health information. While a number of scales measuring the critical health literacy of individuals exist; very few of these are devoted to critical nutrition literacy. More so, these scales target individuals with an advanced level of nutrition education, often gaging their proficiency in information appraisal in relation to principles of evidence-based medical research. The purpose of the present study was to examine the psychometric properties of a newly developed critical nutrition literacy scale (CNL-E) measuring adolescents' perceived proficiency in 'critically evaluating nutrition information from various sources'. METHODS: During spring 2015, more than 1600 tenth graders aged 15-16 years from approximately 60 schools in Norway responded to the five-item questionnaire using an electronic survey system. Applying Rasch analysis approach, we examined the psychometric properties of the CNL-E scale employing the RUMM2030 statistical package. To further investigate the dimensionality of the scale and test the underlying structure, we applied multidimensional Rasch modelling using the ConQuest 4 software and confirmatory factor analysis (CFA) using the Lisrel 9.30 software. RESULTS: In our sample, the CNL-E stood out as a valid, reliable and well-targeted scale with good overall fit to the partial credit parameterization of the polytomous unidimensional Rasch model (PCM). All the items were sufficiently statistically independent, had ordered response categories and showed acceptable individual fit to the PCM. No item displayed within-item bias or differential item functioning (DIF). CONCLUSIONS: From the observed CNL-E sum score, it is possible to draw plausible conclusions about how individuals critically evaluate nutrition information. Efforts to improve communication of nutrition information could benefit from applying validated measures such as the CNL-E scale. The CNL-E scale provides insight into how individuals without an advanced level of nutrition education, such as adolescents, determine the validity and reliability of nutrition information from various sources.


Assuntos
Comunicação em Saúde , Letramento em Saúde/estatística & dados numéricos , Valor Nutritivo , Percepção , Inquéritos e Questionários , Adolescente , Análise Fatorial , Feminino , Humanos , Masculino , Noruega , Psicometria , Reprodutibilidade dos Testes
15.
Eur J Nutr ; 57(3): 1003-1013, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28238109

RESUMO

PURPOSE: Essential fatty acids play a critical role in the growth and development of infants, but little is known about the fatty acid status of populations in low-income countries. The objective was to describe the fatty acid composition of red blood cells (RBC) in breastfeed Nepali infants and a subsample of their mothers and to identify the main sources of fatty acids in the mother's diet, as well as the fatty acid composition of breast milk. METHODS: RBC fatty acid composition was analyzed in a random sample of 303 infants and 72 mother, along with 68 breastmilk samples. Fatty acid profiles of the most important dietary fat sources were analyzed. Information on mother's diet and intake of fat was collected by three 24-h dietary recalls. RESULTS: In infant RBC's, docosahexaenoic acid (DHA) was the main n-3 fatty acid, and arachidonic acid (AA) was the major n-6 fatty acid. Total n-6 PUFA was three times higher than total n-3 PUFA. Height-for-age (HAZ) was positively associated with DHA status and AA status in multivariable models. The concentration of all fatty acids was higher in children, compared to mothers, except Total n-6 PUFA and Linoleic acid (LA) where no differences were found. The mother's energy intake from fat was 13% and cooking oil (sesame, mustard, soybean or sunflower oil) contributed 52% of the fat intake. CONCLUSIONS: RBC-DHA levels in both infants and mother was unexpected high taking into account few dietary DHA sources and the low DHA concentrations in breastmilk.


Assuntos
Aleitamento Materno , Deficiências Nutricionais/etiologia , Dieta com Restrição de Gorduras/efeitos adversos , Eritrócitos/metabolismo , Ácidos Graxos Essenciais/deficiência , Ácidos Graxos/metabolismo , Fenômenos Fisiológicos da Nutrição Materna , Adulto , Aleitamento Materno/etnologia , Desenvolvimento Infantil , Estudos Transversais , Deficiências Nutricionais/etnologia , Deficiências Nutricionais/metabolismo , Deficiências Nutricionais/prevenção & controle , Dieta com Restrição de Gorduras/etnologia , Ácidos Graxos/análise , Ácidos Graxos/sangue , Ácidos Graxos Essenciais/análise , Ácidos Graxos Essenciais/sangue , Ácidos Graxos Essenciais/metabolismo , Feminino , Transtornos do Crescimento/epidemiologia , Transtornos do Crescimento/etnologia , Transtornos do Crescimento/etiologia , Transtornos do Crescimento/metabolismo , Humanos , Lactente , Masculino , Fenômenos Fisiológicos da Nutrição Materna/etnologia , Leite Humano/química , Nepal/epidemiologia , Inquéritos Nutricionais , Óleos de Plantas/uso terapêutico , Prevalência , Magreza/epidemiologia , Magreza/etnologia , Magreza/etiologia , Magreza/metabolismo , Adulto Jovem
16.
J Pediatr Gastroenterol Nutr ; 67(2): 242-249, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29620600

RESUMO

OBJECTIVES: Environmental enteropathy (EE) is likely associated with growth retardation in children, but the association between EE and length velocity z score (LVZ) has not been investigated. The objective of the study was to assess associations between fecal markers for intestinal inflammation and LVZ and whether these associations were influenced by micronutrient adequacy among 9 to 24 months old children in Bhaktapur, Nepal. METHODS: Data were divided into 5 time slots (9-12, 12-15, 15-18, 18-21, and 21-24 months). Anthropometric measurement and dietary assessment (by 24 hour recall) were performed monthly. Mean nutrient density adequacy was calculated based on nutrient density adequacy of 10 micronutrients (thiamin, riboflavin, niacin, vitamin B6, folate, vitamin C, vitamin A, calcium, iron, and zinc). Anti-1-antitrypsin (AAT), myeloperoxidase (MPO), and neopterin (NEO) were measured in stool samples collected at the beginning of each time slot. An EE score was calculated based on all 3 fecal markers. Associations between AAT, MPO, NEO and EE score and LVZ were assessed by multiple linear regression analyses and Generalized Estimating Equations models. RESULTS: Associations between fecal markers and EE score and LVZ were generally weak. EE score and MPO for 3-month and MPO for 6-month growth periods were significantly associated with LVZ from 9 to 24 months. These associations were slightly modified by mean nutrient density adequacy. CONCLUSIONS: EE score and MPO were significantly associated with LVZ in 9 to 24 months old Nepali children. Further studies to establish the usefulness of AAT, MPO, and NEO in assessing EE and growth retardation are warranted.


Assuntos
Transtornos da Nutrição Infantil/epidemiologia , Fezes/química , Micronutrientes/análise , Biomarcadores/análise , Transtornos da Nutrição Infantil/etiologia , Transtornos da Nutrição Infantil/patologia , Transtornos da Nutrição Infantil/prevenção & controle , Fenômenos Fisiológicos da Nutrição Infantil , Pré-Escolar , Estudos de Coortes , Feminino , Humanos , Lactente , Masculino , Micronutrientes/deficiência , Neopterina/análise , Nepal/epidemiologia , Peroxidase/análise , alfa 1-Antitripsina/análise
17.
Nutr J ; 17(1): 17, 2018 02 09.
Artigo em Inglês | MEDLINE | ID: mdl-29426331

RESUMO

BACKGROUND: Culture affects body image and body size perceptions from an early age and in many African countries, overweight has been associated with richness, health, strength, and fertility. The present study investigated body size perceptions and preferences in an African refugee population. METHODS: The cross-sectional study was comprised of 180 and 175 randomly selected Saharawi women and men, respectively, between 18 and 80 years. Stunkard's body figure scale was used to identify self-perceived body size, desired body size and desired body size in the opposite gender. RESULTS: Approximately half of the participants had a correct self-perceived body size; among them 70% did not have a desire to have a smaller body size. Among women who preferred a body size corresponding to overweight in men, 77% also had a desired body size corresponding to overweight; compared to 43% for men. The youngest participants (18-25 years) were the least likely to overestimate their body size in comparison to the older participants (26-45 years and 46-80 years). CONCLUSION: We found an overall preference for an overweight body size, and a significant difference in body size perception associated with age.


Assuntos
Imagem Corporal/psicologia , Tamanho Corporal , Sobrepeso/psicologia , Refugiados/psicologia , Percepção de Tamanho , África do Norte , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Refugiados/estatística & dados numéricos , Inquéritos e Questionários
18.
Nutr J ; 17(1): 70, 2018 07 19.
Artigo em Inglês | MEDLINE | ID: mdl-30025518

RESUMO

BACKGROUND: Long chain polyunsaturated fatty acids (LCPUFA) especially docosahexaenoic acid (DHA) and arachidonic acid (AA) are crucial for normal brain development in utero and in early infancy. Data on fatty acid status and cognitive development in infants and children from low-income countries are scarce. METHODS: We examined the association between the DHA and AA status in infancy (n = 320) and developmental status and cognitive functioning five years later. At five years of age, we measured development by the Ages and Stages Questionnaire 3rd. ed. (ASQ-3) and cognitive functioning by subtests from the neuropsychological test battery NEPSY II. In addition, infant fatty acid composition in red blood cells (RBC) was analyzed. In multiple linear and logistic regression models, we estimated the associations between DHA and AA status in infancy and scores on the ASQ-3 and the NEPSY II subtests. RESULTS: There were no notable associations between infant AA and DHA status, and the scores on the ASQ-3 and the NEPSY II subtests five years later. It should be noted that we found better than expected concentrations of erythrocyte DHA and AA among the infants, and the ASQ scores were left-skewed, which limited the ability to identify associations. CONCLUSION: DHA and AA status in infancy is seemingly not related to neurodevelopment measured 5 years later in this peri-urban population from Nepal.


Assuntos
Ácido Araquidônico/sangue , Desenvolvimento Infantil/fisiologia , Cognição/fisiologia , Ácidos Docosa-Hexaenoicos/sangue , Análise por Conglomerados , Eritrócitos/metabolismo , Feminino , Seguimentos , Humanos , Lactente , Masculino , Nepal , Testes Neuropsicológicos
19.
Public Health Nutr ; 21(2): 355-364, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29037267

RESUMO

OBJECTIVE: The present study aimed to assess infant and young child feeding (IYCF) practices and the tracking of dietary diversity score (DDS), intakes of Fe- and vitamin A-rich foods and meal frequency in a peri-urban area in Nepal. Furthermore, to explore whether sociodemographic factors were associated with tracking patterns of these IYCF practices. DESIGN: Longitudinal study. Monthly food intake was measured by 24 h recall. Four time slots were used (9-12, 13-16, 17-20 and 21-24 months). Tracking of IYCF practices was investigated using generalized estimating equations (GEE) models and Cohen's weighted kappa. Multinominal logistic regression was used to identify determinants for tracking of the IYCF practices. SETTING: Bhaktapur municipality, Nepal. SUBJECTS: Children (n 229) aged 9-24 months, randomly selected. RESULTS: Prevalence of minimum meal frequency was higher than for minimum dietary diversity at all time slots. Tracking based on absolute measures (GEE models) was moderate for DDS (0·48) and meal frequency (0·53), and low for intakes of Fe- (0·23) and vitamin A-rich (0·35) foods. Tracking based on rank measured was moderate for DDS and meal frequency, and fair for Fe- and vitamin A-rich foods. Low socio-economic status significantly increased the odds (OR; 95 % CI) of tracking of low v. high DDS (3·31; 1·44, 7·60) and meal frequency (3·46; 1·54, 7·76). CONCLUSIONS: Low tracking for intakes of Fe- and vitamin A-rich foods implies that interventions to improve these IYCF practices must address underlying causes for irregular intake to have sustainable effects.


Assuntos
Doenças Transmissíveis/epidemiologia , Dieta , Comportamento Alimentar , Desnutrição/epidemiologia , Avaliação Nutricional , Adulto , Aleitamento Materno , Pré-Escolar , Estudos Transversais , Feminino , Humanos , Lactente , Ferro da Dieta/administração & dosagem , Estudos Longitudinais , Masculino , Rememoração Mental , Nepal/epidemiologia , Fatores de Risco , Fatores Socioeconômicos , Inquéritos e Questionários , Vitamina A/administração & dosagem , Adulto Jovem
20.
BMC Pediatr ; 18(1): 328, 2018 10 16.
Artigo em Inglês | MEDLINE | ID: mdl-30326859

RESUMO

BACKGROUND: Food/drinks available to adolescents in schools can influence their dietary behaviours, which once established in adolescence, tend to remain over time. Food outlets' influence near schools, known to provide access to unhealthy food/drinks, may also have lasting effects on consumption behaviours. This study aimed to gain a better understanding of the consumption habits of adolescents in the school arena by comparing different personal characteristics and purchasing behaviours of infrequent and regular school canteen users to those never or seldom using the canteen. METHODS: A convergent mixed methods design collected qualitative and quantitative data in parallel. A cross-sectional quantitative study including 742 adolescents was conducted, with data collected at schools via an online questionnaire. Focus group interviews with students and interviews with school administrators formed the qualitative data content. Quantitative data were analysed using descriptive statistics and logistic regression; thematic content analysis was used to analyse qualitative data. RESULTS: Sixty-seven percent of adolescents reported never/rarely using the school canteen (NEV), whereas 13% used it ≥2 times per week (OFT). When the two groups were compared, we found a significantly higher proportion of the NEV group were female, having parents with a high education, and with a high self-efficacy, whilst a significantly higher proportion of the OFT group consumed salty snacks, baked sweets, and soft-drinks ≥3 times per week, and breakfast at home < 5 days in the school week. The OFT group had significantly higher odds of purchasing food/drink from shops near school during school breaks and before/after school compared to the NEV group (adjusted odds ratio (aOR) = 1.80, 95% CI 1.07-3.01, and aOR = 3.61, 95% CI 2.17-6.01, respectively). The interviews revealed most students ate a home packed lunch, with the remainder purchasing either at the school canteen or at local shops. CONCLUSIONS: Students using the canteen often are frequently purchasing snacks and sugar-soft drinks from shops near school, most likely owing to availability of pocket money and an emerging independence. School authorities must focus upon satisfying canteen users by providing desirable, healthy, and affordable items in order to compete with the appeal of local shops.


Assuntos
Comportamento do Adolescente , Preferências Alimentares , Serviços de Alimentação , Estudantes/psicologia , Adolescente , Criança , Estudos Transversais , Escolaridade , Comportamento Alimentar , Feminino , Humanos , Internet , Masculino , Noruega , Pais/psicologia , Instituições Acadêmicas , Autoeficácia , Fatores Sexuais , Inquéritos e Questionários
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