Detalhe da pesquisa
1.
PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity.
Mol Cell
; 62(2): 222-236, 2016 Apr 21.
Artigo
Inglês
| MEDLINE | ID: mdl-27151440
2.
Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.
Mol Cell
; 53(2): 247-61, 2014 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-24389101
3.
C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis.
Proc Natl Acad Sci U S A
; 111(27): 9899-904, 2014 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-24958854
4.
Deregulation of the HOXA9/MEIS1 axis in acute leukemia.
Curr Opin Hematol
; 23(4): 354-61, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27258906
5.
The same site on the integrase-binding domain of lens epithelium-derived growth factor is a therapeutic target for MLL leukemia and HIV.
Blood
; 124(25): 3730-7, 2014 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-25305204
6.
MLL fusion protein-driven AML is selectively inhibited by targeted disruption of the MLL-PAFc interaction.
Blood
; 122(11): 1914-22, 2013 Sep 12.
Artigo
Inglês
| MEDLINE | ID: mdl-23900238
7.
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia.
PLoS Genet
; 8(6): e1002781, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22737091
8.
Targeting recruitment of disruptor of telomeric silencing 1-like (DOT1L): characterizing the interactions between DOT1L and mixed lineage leukemia (MLL) fusion proteins.
J Biol Chem
; 288(42): 30585-30596, 2013 Oct 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23996074
9.
ECSASB2 mediates MLL degradation during hematopoietic differentiation.
Blood
; 119(5): 1151-61, 2012 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-22174154
10.
Identification and characterization of Hoxa9 binding sites in hematopoietic cells.
Blood
; 119(2): 388-98, 2012 Jan 12.
Artigo
Inglês
| MEDLINE | ID: mdl-22072553
11.
Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia.
Nat Chem Biol
; 8(3): 277-84, 2012 Jan 29.
Artigo
Inglês
| MEDLINE | ID: mdl-22286128
12.
Structural basis of multimer-mediated mayhem.
Cancer Cell
; 9(4): 241-2, 2006 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-16616328
13.
A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.
J Biol Chem
; 287(52): 43410-6, 2012 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23129768
14.
Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Blood
; 117(18): 4759-68, 2011 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21398221
15.
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.
Blood
; 115(1): 38-46, 2010 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-19861679
16.
Dimerization of MLL fusion proteins immortalizes hematopoietic cells.
Cancer Cell
; 4(3): 197-207, 2003 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-14522254
17.
Medical School Without Walls: 50 Years of Regional Campuses at Indiana University School of Medicine.
Acad Med
; 97(12): 1765-1772, 2022 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35976719
18.
Epigenetic dysregulation in cancer.
Am J Pathol
; 175(4): 1353-61, 2009 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-19717641
19.
The PHD fingers of MLL block MLL fusion protein-mediated transformation.
Blood
; 112(12): 4690-3, 2008 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18796627
20.
Chromatin immunoprecipitation (ChIP) for analysis of histone modifications and chromatin-associated proteins.
Methods Mol Biol
; 538: 409-23, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19277579