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1.
Sensors (Basel) ; 17(11)2017 Nov 03.
Artigo em Inglês | MEDLINE | ID: mdl-29099787

RESUMO

This paper investigates the design optimisation of a magnetic field based soft tactile sensor, comprised of a magnet and Hall effect module separated by an elastomer. The aim was to minimise sensitivity of the output force with respect to the input magnetic field; this was achieved by varying the geometry and material properties. Finite element simulations determined the magnetic field and structural behaviour under load. Genetic programming produced phenomenological expressions describing these responses. Optimisation studies constrained by a measurable force and stable loading conditions were conducted; these produced Pareto sets of designs from which the optimal sensor characteristics were selected. The optimisation demonstrated a compromise between sensitivity and the measurable force, a fabricated version of the optimised sensor validated the improvements made using this methodology. The approach presented can be applied in general for optimising soft tactile sensor designs over a range of applications and sensing modes.

2.
Sensors (Basel) ; 16(9)2016 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-27563908

RESUMO

Tactile sensors are essential if robots are to safely interact with the external world and to dexterously manipulate objects. Current tactile sensors have limitations restricting their use, notably being too fragile or having limited performance. Magnetic field-based soft tactile sensors offer a potential improvement, being durable, low cost, accurate and high bandwidth, but they are relatively undeveloped because of the complexities involved in design and calibration. This paper presents a general design methodology for magnetic field-based three-axis soft tactile sensors, enabling researchers to easily develop specific tactile sensors for a variety of applications. All aspects (design, fabrication, calibration and evaluation) of the development of tri-axis soft tactile sensors are presented and discussed. A moving least square approach is used to decouple and convert the magnetic field signal to force output to eliminate non-linearity and cross-talk effects. A case study of a tactile sensor prototype, MagOne, was developed. This achieved a resolution of 1.42 mN in normal force measurement (0.71 mN in shear force), good output repeatability and has a maximum hysteresis error of 3.4%. These results outperform comparable sensors reported previously, highlighting the efficacy of our methodology for sensor design.

3.
Emerg Infect Dis ; 17(1): 123-5, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21192872

RESUMO

To determine antimicrobial drug resistance patterns, we characterized nontyphoidal Salmonella enterica strains isolated in Liverpool, UK, January 2003 through December 2009. Decreased susceptibility to ciprofloxacin was found in 103 (20.9%) of 492 isolates. The lower susceptibility was associated with ciprofloxacin treatment failures and with particular serovars and phage types often acquired during foreign travel.


Assuntos
Anti-Infecciosos/farmacologia , Ciprofloxacina/farmacologia , Farmacorresistência Bacteriana Múltipla , Infecções por Salmonella/microbiologia , Salmonella enterica/efeitos dos fármacos , Viagem , Humanos , Testes de Sensibilidade Microbiana , Ácido Nalidíxico/farmacologia , Salmonella enterica/classificação , Salmonella enteritidis/efeitos dos fármacos , Salmonella typhimurium/efeitos dos fármacos , Reino Unido
4.
J Biomed Mater Res B Appl Biomater ; 105(3): 497-506, 2017 04.
Artigo em Inglês | MEDLINE | ID: mdl-26559657

RESUMO

The lubrication regime in which artificial hip joints operate adds complexity to the prediction of wear, as the joint operates in both the full fluid film regime-specifically the elastohydrodynamic lubrication (EHL) regime-and the mixed or boundary lubrication regimes, where contact between the bearing surfaces results in wear. In this work, a wear model is developed which considers lubrication for the first time via a transient EHL model of metal-on-metal hip replacements. This is a framework to investigate how the change in film thickness influences the wear, which is important to further investigation of the complex wear procedure, including tribocorrosion, in the lubricated hip implants. The wear model applied here is based on the work of Sharif et al. who adapted the Archard wear law by making the wear rate a function of a relative film thickness nominalized by surface roughness for examining wear of industrial gears. In this work, the gait cycle employed in hip simulator tests is computationally investigated and wear is predicted for two sizes of metal-on-metal total hip replacements. The wear results qualitatively predict the typical wear curve obtained from experimental hip simulator tests, with an initial "running-in period" before a lower wear rate is reached. The shape of the wear scar has been simulated on both the acetabular cup and the femoral head bearing surfaces. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 497-506, 2017.


Assuntos
Análise de Falha de Equipamento , Prótese de Quadril , Próteses Articulares Metal-Metal , Modelos Teóricos , Humanos
5.
Sci Rep ; 6: 23702, 2016 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-27025192

RESUMO

The Earth's surface comprises minerals diagnostic of weathering, deposition and erosion. The first continental-scale mineral maps generated from an imaging satellite with spectral bands designed to measure clays, quartz and other minerals were released in 2012 for Australia. Here we show how these satellite mineral maps improve our understanding of weathering, erosional and depositional processes in the context of changing weather, climate and tectonics. The clay composition map shows how kaolinite has developed over tectonically stable continental crust in response to deep weathering during northwardly migrating tropical conditions from 45 to 10 Ma. The same clay composition map, in combination with one sensitive to water content, enables the discrimination of illite from montmorillonite clays that typically develop in large depositional environments over thin (sinking) continental crust such as the Lake Eyre Basin. Cutting across these clay patterns are sandy deserts that developed <10 Ma and are well mapped using another satellite product sensitive to the particle size of silicate minerals. This product can also be used to measure temporal gains/losses of surface clay caused by periodic wind erosion (dust) and rainfall inundation (flood) events. The accuracy and information content of these satellite mineral maps are validated using published data.

6.
J Am Podiatr Med Assoc ; 94(6): 565-72, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15547124

RESUMO

Onychomycosis, most commonly caused by two species of dermatophyte fungi--Trichophyton rubrum and Trichophyton mentagrophytes--is primarily treated with regimens of topical and systemic antifungal medications. This study was undertaken to evaluate in vitro the efficacy of low-voltage direct current as an antifungal agent for treating onychomycosis. Agar plate cultures of T rubrum and T mentagrophytes were subjected to low-voltage direct current electrostimulation, and antifungal effects were observed as zones in the agar around the electrodes lacking fungal growth. Zones devoid of fungal growth were observed for T rubrum and T mentagrophytes around anodes and cathodes in a dose-dependent manner in the current range of 500 microA to 3 mA. Low-voltage direct current electrostimulation has great clinical potential for the treatment of onychomycosis and perhaps other superficial maladies of fungal etiology.


Assuntos
Onicomicose/microbiologia , Tinha dos Pés/microbiologia , Trichophyton/crescimento & desenvolvimento , Estimulação Elétrica/métodos , Terapia por Estimulação Elétrica , Dermatoses do Pé/microbiologia , Dermatoses do Pé/terapia , Humanos , Onicomicose/terapia , Tinha dos Pés/terapia
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