Detalhe da pesquisa
1.
Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Nature
; 629(8013): 927-936, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38588697
2.
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
J Biol Chem
; 297(5): 101335, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34688654
3.
Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
Science
; 384(6700): eadk0775, 2024 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-38843331
4.
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
bioRxiv
; 2023 Dec 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38105998
5.
Targeting the ERK mitogen-activated protein kinase cascade for the treatment of KRAS-mutant pancreatic cancer.
Adv Cancer Res
; 153: 101-130, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35101228
6.
Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.
Cancer Res
; 82(1): 90-104, 2022 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34737214
7.
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Cell Rep
; 35(13): 109291, 2021 06 29.
Artigo
Inglês
| MEDLINE | ID: mdl-34192548
8.
Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion.
Sci Rep
; 10(1): 11958, 2020 07 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32686704