Detalhe da pesquisa
1.
Porin Associates with Tom22 to Regulate the Mitochondrial Protein Gate Assembly.
Mol Cell
; 73(5): 1044-1055.e8, 2019 03 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30738703
2.
Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases.
EMBO J
; 41(17): e111608, 2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35833542
3.
Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock.
Mol Cell
; 67(5): 783-798.e20, 2017 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28886336
4.
Pocket to concavity: a tool for the refinement of protein-ligand binding site shape from alpha spheres.
Bioinformatics
; 39(4)2023 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37086438
5.
Biological Evaluation of Isosteric Applicability of 1,3-Substituted Cuneanes as m-Substituted Benzenes Enabled by Selective Isomerization of 1,4-Substituted Cubanes.
Chemistry
; 30(11): e202303548, 2024 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38012076
6.
Lipid bilayer membrane permeability mechanism of the K-Ras(G12D)-inhibitory bicyclic peptide KS-58 elucidated by molecular dynamics simulations.
Bioorg Med Chem Lett
; 100: 129649, 2024 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38341162
7.
Site Identification and Next Choice Protocol for Hit-to-Lead Optimization.
J Chem Inf Model
; 2024 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38768949
8.
Structural and Energetic Basis for Differential Binding of Ebola and Marburg Virus Glycoproteins to a Bat-Derived Niemann-Pick C1 Protein.
J Infect Dis
; 228(Suppl 7): S479-S487, 2023 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37119290
9.
Lysoglycosphingolipids have the ability to induce cell death through direct PI3K inhibition.
J Neurochem
; 167(6): 753-765, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37975558
10.
Identification of Chemicals That Abrogate Folate-Dependent Inhibition of Starch Accumulation in Non-Photosynthetic Plastids of Arabidopsis.
Plant Cell Physiol
; 64(12): 1551-1562, 2023 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37801291
11.
Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-1.
J Cell Sci
; 134(22)2021 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34676411
12.
AAp-MSMD: Amino Acid Preference Mapping on Protein-Protein Interaction Surfaces Using Mixed-Solvent Molecular Dynamics.
J Chem Inf Model
; 63(24): 7768-7777, 2023 Dec 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38085669
13.
Modeling the structure of the transmembrane domain of T1R3, a subunit of the sweet taste receptor, with neohesperidin dihydrochalcone using molecular dynamics simulation.
Biosci Biotechnol Biochem
; 87(12): 1470-1477, 2023 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37715303
14.
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
BMC Biol
; 20(1): 43, 2022 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35172816
15.
Distinct Profiles of Desensitization of µ-Opioid Receptors Caused by Remifentanil or Fentanyl: In Vitro Assay with Cells and Three-Dimensional Structural Analyses.
Int J Mol Sci
; 24(9)2023 May 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37176075
16.
AlphaFold version 2.0 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys25-Cys192) formation of functional significance for VIPR2.
Biochem Biophys Res Commun
; 636(Pt 1): 10-16, 2022 12 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36332470
17.
MDContactCom: a tool to identify differences of protein molecular dynamics from two MD simulation trajectories in terms of interresidue contacts.
Bioinformatics
; 38(1): 273-274, 2021 12 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34289011
18.
Inverse Mixed-Solvent Molecular Dynamics for Visualization of the Residue Interaction Profile of Molecular Probes.
Int J Mol Sci
; 23(9)2022 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-35563139
19.
[In-Silico Drug Discovery Support-Current Situation and Challenges].
Gan To Kagaku Ryoho
; 49(4): 359-364, 2022 Apr.
Artigo
Japonês
| MEDLINE | ID: mdl-35444115
20.
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.
J Biol Chem
; 295(20): 7154-7167, 2020 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32241910