Detalhe da pesquisa
1.
A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis.
N Engl J Med
; 390(9): 783-794, 2024 Feb 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38381664
2.
Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations.
Am J Hum Genet
; 109(5): 928-943, 2022 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35397207
3.
Immunopathogenesis of Primary Biliary Cholangitis, Primary Sclerosing Cholangitis and Autoimmune Hepatitis: Themes and Concepts.
Gastroenterology
; 166(6): 995-1019, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38342195
4.
Identifying a therapeutic window of opportunity for people living with primary sclerosing cholangitis: Embryology and the overlap of inflammatory bowel disease with immune mediated liver injury.
Hepatology
; 2024 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38743006
5.
Primary biliary cholangitis drug evaluation and regulatory approval: Where do we go from here?
Hepatology
; 2024 Mar 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38506926
6.
Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain?
Hepatology
; 79(1): 39-48, 2024 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37399238
7.
Characterizing the burden of biliary tract cancers across 28 hospitals in Ontario, Canada.
Cancer
; 2024 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38361443
8.
Treatment response and clinical event-free survival in autoimmune hepatitis: a Canadian multicentre cohort study.
J Hepatol
; 2024 Mar 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38527524
9.
Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver.
J Hepatol
; 80(5): 730-743, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38199298
10.
Pursuing living donor liver transplantation improves outcomes of patients with autoimmune liver diseases - An intention-to-treat analysis.
Liver Transpl
; 2024 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38619393
11.
Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis.
Hepatology
; 2023 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-38117036
12.
Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
Hepatology
; 78(2): 397-415, 2023 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37386786
13.
Primary sclerosing cholangitis and overlap features of autoimmune hepatitis: A coming of age or an age-ist problem?
J Hepatol
; 79(2): 567-575, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36870613
14.
New Treatment Paradigms in Primary Biliary Cholangitis.
Clin Gastroenterol Hepatol
; 21(8): 2076-2087, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-36809835
15.
GLIMMER: A Randomized Phase 2b Dose-Ranging Trial of Linerixibat in Primary Biliary Cholangitis Patients With Pruritus.
Clin Gastroenterol Hepatol
; 21(7): 1902-1912.e13, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-36343847
16.
UK-Wide Multicenter Evaluation of Second-line Therapies in Primary Biliary Cholangitis.
Clin Gastroenterol Hepatol
; 21(6): 1561-1570.e13, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35961518
17.
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
Gastroenterology
; 163(6): 1630-1642.e3, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36150526
18.
Ursodeoxycholic Acid Treatment-Induced GLOBE Score Changes Are Associated With Liver Transplantation-Free Survival in Patients With Primary Biliary Cholangitis.
Am J Gastroenterol
; 118(7): 1196-1203, 2023 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36621963
19.
Ethnicity, disease severity, and survival in Canadian patients with primary biliary cholangitis.
Hepatology
; 76(2): 303-316, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35220609
20.
Optimizing therapy in primary biliary cholangitis: Alkaline phosphatase at six months identifies one-year non-responders and predicts survival.
Liver Int
; 43(7): 1497-1506, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37157905