Detalhe da pesquisa
1.
Peptide nucleic acid-dependent artifact can lead to false-positive triplex gene editing signals.
Proc Natl Acad Sci U S A
; 118(45)2021 11 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34732575
2.
Bioengineering of a single long noncoding RNA molecule that carries multiple small RNAs.
Appl Microbiol Biotechnol
; 103(15): 6107-6117, 2019 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-31187211
3.
Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy.
J Pharmacol Exp Ther
; 365(3): 494-506, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29602831
4.
Bioengineered NRF2-siRNA Is Effective to Interfere with NRF2 Pathways and Improve Chemosensitivity of Human Cancer Cells.
Drug Metab Dispos
; 46(1): 2-10, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29061583
5.
MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy.
Drug Metab Dispos
; 44(3): 308-19, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26566807
6.
Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization.
J Pharmacol Exp Ther
; 354(2): 131-41, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26022002
7.
Non-genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia.
Transplant Cell Ther
; 29(3): 164.e1-164.e9, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35995393
8.
Physioxia improves the selectivity of hematopoietic stem cell expansion cultures.
Blood Adv
; 7(14): 3366-3377, 2023 07 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36809781
9.
Nanoradiosensitizer with good tissue penetration and enhances oral cancer radiotherapeutic effect.
Biomaterials
; 289: 121769, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36084485
10.
In vivo fermentation production of humanized noncoding RNAs carrying payload miRNAs for targeted anticancer therapy.
Theranostics
; 11(10): 4858-4871, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33754032
11.
A Novel Bioengineered miR-127 Prodrug Suppresses the Growth and Metastatic Potential of Triple-Negative Breast Cancer Cells.
Cancer Res
; 80(3): 418-429, 2020 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31694904
12.
Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation of target ADME gene expression.
Acta Pharm Sin B
; 9(3): 639-647, 2019 May.
Artigo
Inglês
| MEDLINE | ID: mdl-31193825
13.
Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity.
Mol Ther Nucleic Acids
; 14: 498-508, 2019 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30753993
14.
Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models.
Cancer Lett
; 442: 82-90, 2019 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30389433
15.
Creatine based polymer for codelivery of bioengineered MicroRNA and chemodrugs against breast cancer lung metastasis.
Biomaterials
; 210: 25-40, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31054369
16.
Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4.
Oncotarget
; 10(68): 7251-7275, 2019 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-31921386
17.
Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo.
Int J Pharm
; 547(1-2): 537-544, 2018 Aug 25.
Artigo
Inglês
| MEDLINE | ID: mdl-29894758
18.
Co-targeting of DNA, RNA, and protein molecules provides optimal outcomes for treating osteosarcoma and pulmonary metastasis in spontaneous and experimental metastasis mouse models.
Oncotarget
; 8(19): 30742-30755, 2017 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-28415566
19.
Bioengineering of noncoding RNAs for research agents and therapeutics.
Wiley Interdiscip Rev RNA
; 7(2): 186-97, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26763749