Detalhe da pesquisa
1.
Chronic Lymphocytic Leukemia Therapy Guided by Measurable Residual Disease.
N Engl J Med
; 390(4): 326-337, 2024 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38078508
2.
Ibrutinib and rituximab versus fludarabine, cyclophosphamide, and rituximab for patients with previously untreated chronic lymphocytic leukaemia (FLAIR): interim analysis of a multicentre, open-label, randomised, phase 3 trial.
Lancet Oncol
; 24(5): 535-552, 2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37142374
3.
The addition of vorinostat to lenalidomide maintenance for patients with newly diagnosed multiple myeloma of all ages: results from 'Myeloma XI', a multicentre, open-label, randomised, phase III trial.
Br J Haematol
; 201(2): 267-279, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36541152
4.
Obinutuzumab as consolidation after chemo-immunotherapy: Results of the UK National Cancer Research Institute phase II/III GALACTIC trial.
Br J Haematol
; 199(5): 707-719, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36017875
5.
Thrombosis in patients with myeloma treated in the Myeloma IX and Myeloma XI phase 3 randomized controlled trials.
Blood
; 136(9): 1091-1104, 2020 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32438407
6.
Carfilzomib, lenalidomide, dexamethasone, and cyclophosphamide (KRdc) as induction therapy for transplant-eligible, newly diagnosed multiple myeloma patients (Myeloma XI+): Interim analysis of an open-label randomised controlled trial.
PLoS Med
; 18(1): e1003454, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33428632
7.
Early relapse after high-dose melphalan autologous stem cell transplant predicts inferior survival and is associated with high disease burden and genetically high-risk disease in multiple myeloma.
Br J Haematol
; 193(3): 551-555, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32524584
8.
Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project.
BMC Med
; 19(1): 251, 2021 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-34696781
9.
Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial.
Lancet Oncol
; 20(1): 57-73, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30559051
10.
The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long-term follow-up results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial.
Br J Haematol
; 185(3): 450-467, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30729512
11.
Redefining nonmeasurable multiple myeloma using mass spectrometry.
Blood
; 139(6): 946-950, 2022 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34871382
12.
Long-term follow-up of 415 patients with chronic lymphocytic leukemia treated with fludarabine and cyclophosphamide-based chemoimmunotherapy in the frontline ADMIRE and ARCTIC trials: A comprehensive assessment of prognostic factors.
Am J Hematol
; 97(5): E168-E171, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35108412
13.
COSMIC, chemotherapy plus ofatumumab at standard or mega-dose in chronic lymphocytic leukaemia, a phase II randomised study.
Br J Haematol
; 194(3): 646-650, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34028800
14.
Trial re-investment to build better research for better impact.
Lancet
; 394(10199): 635-636, 2019 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31448733
15.
Association of genetic variants with patient reported quality of life and pain experience in patients in the UK NCRI Myeloma X Relapse [Intensive]) trial; an exploratory study.
Bone Marrow Transplant
; 57(10): 1507-1513, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35768571
16.
Minimal Residual Disease After Autologous Stem-Cell Transplant for Patients With Myeloma: Prognostic Significance and the Impact of Lenalidomide Maintenance and Molecular Risk.
J Clin Oncol
; 40(25): 2889-2900, 2022 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35377708
17.
Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III trial.
BMJ Open
; 12(6): e056147, 2022 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35654466
18.
Risk and response adapted therapy following autologous stem cell transplant in patients with newly diagnosed multiple myeloma (RADAR (UK-MRA Myeloma XV Trial): study protocol for a phase II/III randomised controlled trial.
BMJ Open
; 12(11): e063037, 2022 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36396306
19.
A platform trial in practice: adding a new experimental research arm to the ongoing confirmatory FLAIR trial in chronic lymphocytic leukaemia.
Trials
; 22(1): 38, 2021 Jan 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33419469
20.
TP53 Mutations with Low Variant Allele Frequency Predict Short Survival in Chronic Lymphocytic Leukemia.
Clin Cancer Res
; 27(20): 5566-5575, 2021 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34285062