Detalhe da pesquisa
1.
Chk1 loss creates replication barriers that compromise cell survival independently of excess origin firing.
EMBO J
; 38(16): e101284, 2019 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31294866
2.
DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF.
PLoS Genet
; 14(7): e1007541, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30059501
3.
Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress.
Int J Mol Sci
; 22(8)2021 Apr 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33920223
4.
Low Replicative Stress Triggers Cell-Type Specific Inheritable Advanced Replication Timing.
Int J Mol Sci
; 22(9)2021 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34066960
5.
A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres.
Int J Mol Sci
; 22(5)2021 Feb 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33673424
6.
DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status.
Haematologica
; 103(6): 1038-1046, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29567785
7.
The Protective Role of Dormant Origins in Response to Replicative Stress.
Int J Mol Sci
; 19(11)2018 Nov 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30424570
8.
DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.
EMBO J
; 32(15): 2172-85, 2013 Jul 31.
Artigo
Inglês
| MEDLINE | ID: mdl-23799366
9.
Analysis of DNA Replication by Optical Mapping in Nanochannels.
Small
; 12(43): 5963-5970, 2016 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-27624455
10.
A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study.
BMC Cancer
; 14: 850, 2014 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-25409685
11.
Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants.
Life Sci Alliance
; 7(1)2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37891003
12.
Cytidine Deaminase Resolves Replicative Stress and Protects Pancreatic Cancer from DNA-Targeting Drugs.
Cancer Res
; 84(7): 1013-1028, 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38294491
13.
DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability.
Proc Natl Acad Sci U S A
; 107(30): 13390-5, 2010 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-20624954
14.
The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.
NAR Cancer
; 5(2): zcad011, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-36915289
15.
High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients.
Genes (Basel)
; 14(6)2023 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37372450
16.
Aberrant expression of alternative DNA polymerases: a source of mutator phenotype as well as replicative stress in cancer.
Semin Cancer Biol
; 20(5): 312-9, 2010 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-20934518
17.
RIP140 regulates POLK gene expression and the response to alkylating drugs in colon cancer cells.
Cancer Drug Resist
; 5(2): 401-414, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35800380
18.
Active site mutations in mammalian DNA polymerase delta alter accuracy and replication fork progression.
J Biol Chem
; 285(42): 32264-72, 2010 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-20628184
19.
The Heritability of Replication Problems.
Cells
; 10(6)2021 06 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34207969
20.
Recent Advances in Enhancing the Therapeutic Index of PARP Inhibitors in Breast Cancer.
Cancers (Basel)
; 13(16)2021 Aug 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34439286