Detalhe da pesquisa
1.
Interdependence of the rad50 hook and globular domain functions.
Mol Cell
; 57(3): 479-91, 2015 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25601756
2.
Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis.
PLoS Genet
; 16(3): e1008422, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32187176
3.
The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.
Genes Dev
; 28(5): 451-62, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24532689
4.
The telomere-binding protein Rif2 and ATP-bound Rad50 have opposing roles in the activation of yeast Tel1ATM kinase.
J Biol Chem
; 294(49): 18846-18852, 2019 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31640985
5.
Cohesin association to replication sites depends on rad50 and promotes fork restart.
Mol Cell
; 48(1): 98-108, 2012 Oct 12.
Artigo
Inglês
| MEDLINE | ID: mdl-22885006
6.
Chronic Interferon Stimulated Gene Transcription Promotes Oncogene Induced Breast Cancer.
bioRxiv
; 2023 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37905095
7.
RTEL1 influences the abundance and localization of TERRA RNA.
Nat Commun
; 12(1): 3016, 2021 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34021146
8.
The Rad50 hook domain is a critical determinant of Mre11 complex functions.
Nat Struct Mol Biol
; 12(5): 403-7, 2005 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15852023
9.
A Disease-Causing Single Amino Acid Deletion in the Coiled-Coil Domain of RAD50 Impairs MRE11 Complex Functions in Yeast and Humans.
Cell Rep
; 33(13): 108559, 2020 12 29.
Artigo
Inglês
| MEDLINE | ID: mdl-33378670
10.
Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.
Nucleic Acids Res
; 35(9): 3053-63, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17452369
11.
Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks.
Cell Rep
; 28(6): 1564-1573.e3, 2019 08 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31390569
12.
Eukaryotic Rad50 functions as a rod-shaped dimer.
Nat Struct Mol Biol
; 24(3): 248-257, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28134932
13.
Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy.
Cancer Discov
; 4(9): 1014-21, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24934408
14.
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions.
Nat Struct Mol Biol
; 18(10): 1124-31, 2011 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21892167
15.
The spacer region of XPG mediates recruitment to nucleotide excision repair complexes and determines substrate specificity.
J Biol Chem
; 280(8): 7030-7, 2005 Feb 25.
Artigo
Inglês
| MEDLINE | ID: mdl-15590680
16.
Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG.
J Biol Chem
; 278(21): 19500-8, 2003 May 23.
Artigo
Inglês
| MEDLINE | ID: mdl-12644470