Detalhe da pesquisa
1.
Paracrine Wnt5a-ß-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization.
Immunity
; 48(1): 147-160.e7, 2018 01 16.
Artigo
Inglês
| MEDLINE | ID: mdl-29343435
2.
Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development.
FASEB J
; 28(3): 1248-67, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24308972
3.
A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression.
Sci Immunol
; 9(95): eadi4191, 2024 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-38728412
4.
A SREBF2-dependent gene program drives an immunotolerant dendritic cell population during cancer progression.
bioRxiv
; 2023 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37162965
5.
Identification of a Germline Pyrin Variant in a Metastatic Melanoma Patient With Multiple Spontaneous Regressions and Immune-related Adverse Events.
J Immunother
; 45(6): 284-290, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35621992
6.
Tumor-intrinsic NLRP3-HSP70-TLR4 axis drives premetastatic niche development and hyperprogression during anti-PD-1 immunotherapy.
Sci Transl Med
; 14(672): eabq7019, 2022 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36417489
7.
Overcoming Immunotherapy Resistance by Targeting the Tumor-Intrinsic NLRP3-HSP70 Signaling Axis.
Cancers (Basel)
; 13(19)2021 Sep 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34638239
8.
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.
Cell Rep
; 35(5): 109071, 2021 05 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33951424
9.
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy.
J Clin Invest
; 130(5): 2570-2586, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32017708
10.
TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti-PD-1 Therapy in Melanoma.
Cancer Immunol Res
; 7(10): 1672-1686, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31451482
11.
MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.
Nat Commun
; 10(1): 1515, 2019 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30944303
12.
Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response.
J Clin Invest
; 128(6): 2356-2369, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29708510
13.
Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGFß Inhibitor Sequencing in Melanoma.
Cancer Immunol Res
; 6(12): 1459-1471, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30209062
14.
Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking.
Nat Commun
; 9(1): 1988, 2018 05 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29777108
15.
Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy.
Cancer Immunol Res
; 3(9): 1082-95, 2015 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-26041736
16.
Early Carcinogenesis Involves the Establishment of Immune Privilege via Intrinsic and Extrinsic Regulation of Indoleamine 2,3-dioxygenase-1: Translational Implications in Cancer Immunotherapy.
Front Immunol
; 5: 438, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25339948
17.
Type III TGF-ß receptor downregulation generates an immunotolerant tumor microenvironment.
J Clin Invest
; 123(9): 3925-40, 2013 09.
Artigo
Inglês
| MEDLINE | ID: mdl-23925295
18.
Type III TGF-ß receptor enhances colon cancer cell migration and anchorage-independent growth.
Neoplasia
; 13(8): 758-70, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21847367