Detalhe da pesquisa
1.
Identification of novel loci affecting circulating chromogranins and related peptides.
Hum Mol Genet
; 26(1): 233-242, 2017 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28011710
2.
Chromogranin B: intra- and extra-cellular mechanisms to regulate catecholamine storage and release, in catecholaminergic cells and organisms.
J Neurochem
; 129(1): 48-59, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24266713
3.
Naturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease.
Cell Mol Neurobiol
; 30(8): 1395-400, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21061160
4.
Genetic cathepsin B deficiency reduces beta-amyloid in transgenic mice expressing human wild-type amyloid precursor protein.
Biochem Biophys Res Commun
; 386(2): 284-8, 2009 Aug 21.
Artigo
Inglês
| MEDLINE | ID: mdl-19501042
5.
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Science
; 364(6436)2019 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30975860
6.
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro.
ACS Chem Biol
; 13(9): 2513-2521, 2018 09 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30085657
7.
Neuroproteases in peptide neurotransmission and neurodegenerative diseases: applications to drug discovery research.
BioDrugs
; 20(2): 105-19, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16626168
8.
Demonstration of GTG as an endogenous initiation codon for a human mRNA transcript revealed by molecular cloning of the serpin endopin 2B.
J Biol Chem
; 2004 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-15316004
9.
Novel chromaffin granule serpins, endopin 1 and endopin 2: endogenous protease inhibitors with distinct target protease specificities.
Ann N Y Acad Sci
; 971: 426-44, 2002 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-12438161
10.
Regulation of cellular alpha-MSH and beta-endorphin during stimulated secretion from intermediate pituitary cells: involvement of aspartyl and cysteine proteases in the control of cellular levels of alpha-MSH and beta-endorphin.
Peptides
; 23(8): 1409-18, 2002 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12182941
11.
Regulation of ACTH levels in anterior pituitary cells during stimulated secretion: evidence for aspartyl and cysteine proteases in the cellular metabolism of ACTH.
Peptides
; 24(5): 717-25, 2003 May.
Artigo
Inglês
| MEDLINE | ID: mdl-12895658
12.
Selective roles for the PC2 processing enzyme in the regulation of peptide neurotransmitter levels in brain and peripheral neuroendocrine tissues of PC2 deficient mice.
Neuropeptides
; 37(3): 140-8, 2003 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-12860111
13.
Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure.
J Hypertens
; 30(10): 1961-9, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22871890
14.
Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein.
J Biol Chem
; 283(12): 7745-53, 2008 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-18184658
15.
Sorting of the neuroendocrine secretory protein Secretogranin II into the regulated secretory pathway: role of N- and C-terminal alpha-helical domains.
J Biol Chem
; 283(17): 11807-22, 2008 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-18299326
16.
Multiple domains of endopin 2A for serpin cross-class inhibition of papain.
Arch Biochem Biophys
; 461(2): 219-24, 2007 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17451636
17.
Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics.
Biol Chem
; 388(9): 979-83, 2007 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-17696783
18.
Primary culture of bovine chromaffin cells.
Nat Protoc
; 2(5): 1248-53, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17546020
19.
Protease pathways in peptide neurotransmission and neurodegenerative diseases.
Cell Mol Neurobiol
; 26(4-6): 449-69, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-16724274
20.
Unique neuronal functions of cathepsin L and cathepsin B in secretory vesicles: biosynthesis of peptides in neurotransmission and neurodegenerative disease.
Biol Chem
; 387(10-11): 1429-39, 2006.
Artigo
Inglês
| MEDLINE | ID: mdl-17081116