Detalhe da pesquisa
1.
Small-molecule inhibitors of human mitochondrial DNA transcription.
Nature
; 588(7839): 712-716, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33328633
2.
Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase.
Mol Cell
; 49(6): 1159-66, 2013 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23478441
3.
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells.
Nat Microbiol
; 9(6): 1499-1512, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38548922
4.
A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors.
EMBO Mol Med
; 15(3): e16959, 2023 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36740985
5.
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections.
Nat Commun
; 14(1): 6785, 2023 10 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37880247
6.
Dual-specificity phosphatases are targets of the Wnt/ß-catenin pathway and candidate mediators of ß-catenin/Ras signaling interactions.
Biol Chem
; 393(10): 1183-91, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23089536
7.
GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.
Elife
; 112022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35229715
8.
Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.
EMBO Mol Med
; 13(1): e13426, 2021 01 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33179852
9.
Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis.
Nat Commun
; 11(1): 687, 2020 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32019926
10.
Hexosamine Pathway Activation Improves Protein Homeostasis through the Integrated Stress Response.
iScience
; 23(3): 100887, 2020 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32086012
11.
The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.
FEBS Lett
; 594(1): 175-188, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31365120
12.
Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug-Target Interactions.
Methods Mol Biol
; 1953: 23-31, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30912013
13.
Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.
Oncotarget
; 9(11): 9838-9851, 2018 Feb 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29515774
14.
Bortezomib resistance mutations in PSMB5 determine response to second-generation proteasome inhibitors in multiple myeloma.
Leukemia
; 35(3): 887-892, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32690882
15.
DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation.
Dev Cell
; 28(6): 697-710, 2014 Mar 31.
Artigo
Inglês
| MEDLINE | ID: mdl-24613396