Pesquisa | Secretaria de Estado da Saúde

1.

The Tukey trend test: Multiplicity adjustment using multiple marginal models.

Schaarschmidt, Frank; Ritz, Christian; Hothorn, Ludwig A.

Biometrics ; 78(2): 789-797, 2022 06.

Artigo Inglês | MEDLINE | ID: mdl-33559878

2.

Using historical control data in bioassays for regulatory toxicology.

Kluxen, Felix M; Weber, Klaus; Strupp, Christian; Jensen, Signe M; Hothorn, Ludwig A; Garcin, Jean-Christophe; Hofmann, Thomas.

Regul Toxicol Pharmacol ; 125: 105024, 2021 Oct.

Artigo Inglês | MEDLINE | ID: mdl-34364928

3.

Mechanistic basis for the activation of plant membrane receptor kinases by SERK-family coreceptors.

Hohmann, Ulrich; Santiago, Julia; Nicolet, Joël; Olsson, Vilde; Spiga, Fabio M; Hothorn, Ludwig A; Butenko, Melinka A; Hothorn, Michael.

Proc Natl Acad Sci U S A ; 115(13): 3488-3493, 2018 03 27.

Artigo Inglês | MEDLINE | ID: mdl-29531026

4.

Alternatives to statistical decision trees in regulatory (eco-)toxicological bioassays.

Kluxen, Felix M; Hothorn, Ludwig A.

Arch Toxicol ; 94(4): 1135-1149, 2020 04.

Artigo Inglês | MEDLINE | ID: mdl-32193567

5.

Use compatibility intervals in regulatory toxicology.

Hothorn, Ludwig A.

Regul Toxicol Pharmacol ; 116: 104720, 2020 Oct.

Artigo Inglês | MEDLINE | ID: mdl-32645430

6.

Multi-arm trials with multiple primary endpoints and missing values.

Hasler, Mario; Hothorn, Ludwig A.

Stat Med ; 37(5): 710-721, 2018 02 28.

Artigo Inglês | MEDLINE | ID: mdl-29108137

7.

Simultaneous small-sample comparisons in longitudinal or multi-endpoint trials using multiple marginal models.

Pallmann, Philip; Ritz, Christian; Hothorn, Ludwig A.

Stat Med ; 37(9): 1562-1576, 2018 04 30.

Artigo Inglês | MEDLINE | ID: mdl-29444546

8.

Identification of the minimum effective dose for normally distributed data using a Bayesian variable selection approach.

Otava, Martin; Shkedy, Ziv; Hothorn, Ludwig A; Talloen, Willem; Gerhard, Daniel; Kasim, Adetayo.

J Biopharm Stat ; 27(6): 1073-1088, 2017.

Artigo Inglês | MEDLINE | ID: mdl-28328286

9.

A General Framework for the Evaluation of Genetic Association Studies Using Multiple Marginal Models.

Kitsche, Andreas; Ritz, Christian; Hothorn, Ludwig A.

Hum Hered ; 81(3): 150-172, 2016.

Artigo Inglês | MEDLINE | ID: mdl-28002824

10.

Boxplots for grouped and clustered data in toxicology.

Pallmann, Philip; Hothorn, Ludwig A.

Arch Toxicol ; 90(7): 1631-8, 2016 Jul.

Artigo Inglês | MEDLINE | ID: mdl-26438403

11.

Testing for qualitative interaction using ratios of treatment differences.

Kitsche, Andreas; Hothorn, Ludwig A.

Stat Med ; 33(9): 1477-89, 2014 Apr 30.

Artigo Inglês | MEDLINE | ID: mdl-24302387

12.

Statistical methods and software for validation studies on new in vitro toxicity assays.

Schaarschmidt, Frank; Hothorn, Ludwig A.

Altern Lab Anim ; 42(5): 319-26, 2014 Nov.

Artigo Inglês | MEDLINE | ID: mdl-25413292

13.

Statistical analysis of the hen's egg test for micronucleus induction (HET-MN assay).

Hothorn, Ludwig A; Reisinger, Kerstin; Wolf, Thorsten; Poth, Albrecht; Fieblinger, Dagmar; Liebsch, Manfred; Pirow, Ralph.

Mutat Res ; 757(1): 68-78, 2013 Sep 18.

Artigo Inglês | MEDLINE | ID: mdl-23892231

14.

Statistical evaluation of toxicological assays: Dunnett or Williams test-take both.

Jaki, Thomas; Hothorn, Ludwig A.

Arch Toxicol ; 87(11): 1901-1910, 2013 Nov.

Artigo Inglês | MEDLINE | ID: mdl-23652543

15.

Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections.

Senti, Gabriela; Crameri, Reto; Kuster, Daniela; Johansen, Pål; Martinez-Gomez, Julia M; Graf, Nicole; Steiner, Martin; Hothorn, Ludwig A; Grönlund, Hans; Tivig, Christine; Zaleska, Anna; Soyer, Ozge; van Hage, Marianne; Akdis, Cezmi A; Akdis, Mübeccel; Rose, Horst; Kündig, Thomas M.

J Allergy Clin Immunol ; 129(5): 1290-6, 2012 May.

Artigo Inglês | MEDLINE | ID: mdl-22464647

16.

Model-specific tests on variance heterogeneity for detection of potentially interacting genetic loci.

Hothorn, Ludwig A; Libiger, Ondrej; Gerhard, Daniel.

BMC Genet ; 13: 59, 2012 Jul 18.

Artigo Inglês | MEDLINE | ID: mdl-22808950

17.

Two new approaches to improve the analysis of BALB/c 3T3 cell transformation assay data.

Hoffmann, Sebastian; Hothorn, Ludwig A; Edler, Lutz; Kleensang, André; Suzuki, Masaya; Phrakonkham, Pascal; Gerhard, Daniel.

Mutat Res ; 744(1): 36-41, 2012 Apr 11.

Artigo Inglês | MEDLINE | ID: mdl-22178130

18.

Statistical evaluation of mortality in long-term carcinogenicity bioassays using a Williams-type procedure.

Herberich, Esther; Hothorn, Ludwig A.

Regul Toxicol Pharmacol ; 64(1): 26-34, 2012 Oct.

Artigo Inglês | MEDLINE | ID: mdl-22749913

19.

HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides.

Roman, Andra-Octavia; Jimenez-Sandoval, Pedro; Augustin, Sebastian; Broyart, Caroline; Hothorn, Ludwig A; Santiago, Julia.

Nat Commun ; 13(1): 876, 2022 02 15.

Artigo Inglês | MEDLINE | ID: mdl-35169143

20.

Rank transformation in Haseman-Elston regression using scores for location-scale alternatives.

Gerhard, Daniel; Hothorn, Ludwig A.

Hum Hered ; 69(3): 143-51, 2010.

Artigo Inglês | MEDLINE | ID: mdl-20029226

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