Detalhe da pesquisa
1.
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Cell
; 178(4): 949-963.e18, 2019 08 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31353221
2.
The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory.
Immunity
; 49(4): 615-626.e6, 2018 10 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30332629
3.
Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex.
Mol Cell Proteomics
; 23(3): 100741, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38387774
4.
Dual-mechanism estrogen receptor inhibitors.
Proc Natl Acad Sci U S A
; 118(35)2021 08 31.
Artigo
Inglês
| MEDLINE | ID: mdl-34452998
5.
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.
Nat Chem Biol
; 17(3): 307-316, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33510451
6.
The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.
Int J Mol Sci
; 24(1)2022 Dec 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36613751
7.
A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium.
Chem Res Toxicol
; 34(2): 313-329, 2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33405908
8.
Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition.
Bioorg Med Chem Lett
; 30(16): 127293, 2020 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32631515
9.
Corticosteroid Action in the Brain: The Potential of Selective Receptor Modulation.
Neuroendocrinology
; 109(3): 266-276, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30884490
10.
The effects of all-trans retinoic acid on estrogen receptor signaling in the estrogen-sensitive MCF/BUS subline.
J Recept Signal Transduct Res
; 38(2): 112-121, 2018 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-29447503
11.
Predictive features of ligand-specific signaling through the estrogen receptor.
Mol Syst Biol
; 12(4): 864, 2016 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-27107013
12.
Characterization of the differential coregulator binding signatures of the Retinoic Acid Receptor subtypes upon (ant)agonist action.
Biochim Biophys Acta Proteins Proteom
; 1865(9): 1195-1206, 2017 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-28642153
13.
Destabilization of the torsioned conformation of a ligand side chain inverts the LXRß activity.
Biochim Biophys Acta
; 1851(12): 1577-86, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26434697
14.
Co-activator candidate interactions for orphan nuclear receptor NR2E1.
BMC Genomics
; 17(1): 832, 2016 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-27782803
15.
The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors.
Breast Cancer Res
; 18(1): 123, 2016 12 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27927249
16.
Differential modulation of FXR activity by chlorophacinone and ivermectin analogs.
Toxicol Appl Pharmacol
; 313: 138-148, 2016 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27773686
17.
Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator.
Proc Natl Acad Sci U S A
; 110(19): 7910-5, 2013 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-23613579
18.
Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.
Chem Res Toxicol
; 27(2): 304-308, 2014 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-24460184
19.
Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure.
Chem Res Toxicol
; 26(3): 336-46, 2013 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-23383871
20.
Peripheral glucocorticoid receptor antagonism by relacorilant with modest HPA axis disinhibition.
J Endocrinol
; 256(2)2023 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36445262