Detalhe da pesquisa
1.
Irgm2 and Gate-16 cooperatively dampen Gram-negative bacteria-induced caspase-11 response.
EMBO Rep
; 21(11): e50829, 2020 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33124769
2.
RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.
Proc Natl Acad Sci U S A
; 112(33): E4581-90, 2015 Aug 18.
Artigo
Inglês
| MEDLINE | ID: mdl-26240314
3.
The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7.
Cell Microbiol
; 18(2): 244-59, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26247512
4.
Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.
BMC Biol
; 14: 33, 2016 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27098192
5.
Identification of the microsporidian Encephalitozoon cuniculi as a new target of the IFNγ-inducible IRG resistance system.
PLoS Pathog
; 10(10): e1004449, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25356593
6.
A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins.
PLoS Biol
; 10(7): e1001358, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22802726
7.
Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.
J Immunol
; 191(4): 1765-74, 2013 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23842753
8.
Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy.
PLoS Pathog
; 8(3): e1002567, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22457617
9.
The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii.
Cell Microbiol
; 14(12): 1921-33, 2012 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-22906355
10.
Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.
PLoS Biol
; 8(12): e1000576, 2010 Dec 21.
Artigo
Inglês
| MEDLINE | ID: mdl-21203588
11.
Correction: Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii.
PLoS Biol
; 13(7): e1002199, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-26158675
12.
Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.
J Biol Chem
; 286(35): 30471-30480, 2011 Sep 02.
Artigo
Inglês
| MEDLINE | ID: mdl-21757726
13.
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii.
EMBO J
; 27(19): 2495-509, 2008 Oct 08.
Artigo
Inglês
| MEDLINE | ID: mdl-18772884
14.
UNC93B1 mediates host resistance to infection with Toxoplasma gondii.
PLoS Pathog
; 6(8): e1001071, 2010 Aug 26.
Artigo
Inglês
| MEDLINE | ID: mdl-20865117
15.
Death and resurrection of the human IRGM gene.
PLoS Genet
; 5(3): e1000403, 2009 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-19266026
16.
The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii.
BMC Biol
; 9: 7, 2011 Jan 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21276251
17.
The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens.
Mamm Genome
; 22(1-2): 43-54, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21052678
18.
Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.
PLoS Pathog
; 5(2): e1000288, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19197351
19.
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole.
Cell Microbiol
; 12(7): 939-61, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20109161
20.
Virulent Toxoplasma gondii evade immunity-related GTPase-mediated parasite vacuole disruption within primed macrophages.
J Immunol
; 182(6): 3775-81, 2009 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19265156