Detalhe da pesquisa
1.
PolyQ-expanded ataxin-2 aggregation impairs cellular processing-body homeostasis via sequestering the RNA helicase DDX6.
J Biol Chem
; : 107413, 2024 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38810698
2.
PABPN1 aggregation is driven by Ala expansion and poly(A)-RNA binding, leading to CFIm25 sequestration that impairs alternative polyadenylation.
J Biol Chem
; 299(8): 105019, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37422193
3.
RNA-assisted sequestration of RNA-binding proteins by cytoplasmic inclusions of the C-terminal 35-kDa fragment of TDP-43.
J Cell Sci
; 135(6)2022 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35142363
4.
Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents.
Bioorg Chem
; 143: 107022, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38142558
5.
Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.
Bioorg Chem
; 144: 107113, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38232685
6.
Goal-Guided Graph Attention Network with Interactive State Refinement for Multi-Agent Trajectory Prediction.
Sensors (Basel)
; 24(7)2024 Mar 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38610277
7.
Effect of ZrS2 load single/dual-atom catalysts on the hydrogen evolution reaction: A first-principles study.
J Comput Chem
; 44(1): 15-26, 2023 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36169382
8.
O-GlcNAcylation of TDP-43 suppresses proteinopathies and promotes TDP-43's mRNA splicing activity.
EMBO Rep
; 22(6): e51649, 2021 06 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33855783
9.
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77.
Bioorg Chem
; 140: 106795, 2023 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37657195
10.
Coaggregation of polyglutamine (polyQ) proteins is mediated by polyQ-tract interactions and impairs cellular proteostasis.
Acta Biochim Biophys Sin (Shanghai)
; 55(5): 736-748, 2023 May 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37171184
11.
Coumarins from Jinhua Finger Citron: Separation by Liquid-Liquid Chromatography and Potential Antitumor Activity.
Molecules
; 28(19)2023 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37836760
12.
Approved Small-Molecule ATP-Competitive Kinases Drugs Containing Indole/Azaindole/Oxindole Scaffolds: R&D and Binding Patterns Profiling.
Molecules
; 28(3)2023 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36770611
13.
Application of MoS2-FeS functional carrier loaded Ni single-atom catalysts on HER: first principle.
Nanotechnology
; 33(27)2022 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35344947
14.
Effects of rocuronium dosage on intraoperative neurophysiological monitoring in patients undergoing spinal surgery.
J Clin Pharm Ther
; 47(3): 313-320, 2022 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-34750839
15.
Synthesis and Biological Evaluation of 1-(2-(6-Methoxynaphthalen-2-yl)-6-methylnicotinoyl)-4-Substituted Semicarbazides/Thiosemicarbazides as Anti-Tumor Nur77 Modulators.
Molecules
; 27(5)2022 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35268797
16.
Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation.
Biochem J
; 477(21): 4295-4312, 2020 11 13.
Artigo
Inglês
| MEDLINE | ID: mdl-33094816
17.
Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent.
J Enzyme Inhib Med Chem
; 36(1): 1436-1453, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34229558
18.
Synthesis and Antiproliferative Activity of New Thiosemicarboxamide Derivatives.
Chem Biodivers
; 18(12): e2100671, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34738709
19.
Design, Synthesis and Anticancer Activity of a New Series of N-aryl-N'-[4-(pyridin-2-ylmethoxy)benzyl]urea Derivatives.
Molecules
; 26(12)2021 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34201326
20.
The Impact of the COVID-19 Pandemic and the Importance of Telemedicine in Managing Acute ST Segment Elevation Myocardial Infarction Patients: Preliminary Experience and Literature Review.
J Med Syst
; 45(1): 9, 2021 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33404890