Detalhe da pesquisa
1.
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.
Cell
; 163(4): 947-59, 2015 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26593423
2.
Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability.
Cell
; 159(7): 1538-48, 2014 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25483776
3.
Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates.
Mol Cell
; 81(22): 4747-4756.e7, 2021 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34648747
4.
The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing.
Cell
; 149(6): 1221-32, 2012 Jun 08.
Artigo
Inglês
| MEDLINE | ID: mdl-22682245
5.
C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency.
EMBO J
; 41(11): e109324, 2022 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35471583
6.
Engineering of efficiency-enhanced Cas9 and base editors with improved gene therapy efficacies.
Mol Ther
; 31(3): 744-759, 2023 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36457249
7.
CRISPR/Cas9-induced structural variations expand in T lymphocytes in vivo.
Nucleic Acids Res
; 50(19): 11128-11137, 2022 10 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36243978
8.
In-depth assessment of the PAM compatibility and editing activities of Cas9 variants.
Nucleic Acids Res
; 49(15): 8785-8795, 2021 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34133740
9.
FACT interacts with Set3 HDAC and fine-tunes GAL1 transcription in response to environmental stimulation.
Nucleic Acids Res
; 49(10): 5502-5519, 2021 06 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33963860
10.
Global detection of DNA repair outcomes induced by CRISPR-Cas9.
Nucleic Acids Res
; 49(15): 8732-8742, 2021 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34365511
11.
The origin of unwanted editing byproducts in gene editing.
Acta Biochim Biophys Sin (Shanghai)
; 54(6): 767-781, 2022 May 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35643959
12.
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
Nature
; 525(7567): 134-139, 2015 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-26308889
13.
Highly sensitive and unbiased approach for elucidating antibody repertoires.
Proc Natl Acad Sci U S A
; 113(28): 7846-51, 2016 07 12.
Artigo
Inglês
| MEDLINE | ID: mdl-27354528
14.
Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells.
J Biol Chem
; 292(12): 4777-4788, 2017 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-28159842
15.
Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe.
J Biol Chem
; 292(15): 6056-6075, 2017 04 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28223353
16.
Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.
Proc Natl Acad Sci U S A
; 111(28): 10269-74, 2014 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24982162
17.
Fork coupling directs DNA replication elongation and termination.
Science
; 383(6688): 1215-1222, 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38484065
18.
Cohesin maintains replication timing to suppress DNA damage on cancer genes.
Nat Genet
; 55(8): 1347-1358, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37500731
19.
Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor.
Protein Cell
; 14(6): 416-432, 2023 06 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37285261
20.
Comprehensive assessment of miniature CRISPR-Cas12f nucleases for gene disruption.
Nat Commun
; 13(1): 5623, 2022 09 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36153319