Detalhe da pesquisa
1.
An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor.
Cell
; 174(5): 1158-1171.e19, 2018 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30057110
2.
Multivalent Small-Molecule Pan-RAS Inhibitors.
Cell
; 168(5): 878-889.e29, 2017 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28235199
3.
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Mol Cell
; 70(3): 408-421.e8, 2018 05 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29628311
4.
The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Nature
; 574(7777): 249-253, 2019 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31578523
5.
Mossy Cells in the Dorsal and Ventral Dentate Gyrus Differ in Their Patterns of Axonal Projections.
J Neurosci
; 41(5): 991-1004, 2021 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33268544
6.
Development of BET inhibitors as potential treatments for cancer: A search for structural diversity.
Bioorg Med Chem Lett
; 44: 128108, 2021 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33991625
7.
Visible light sensorless adaptive optics for retinal structure and fluorescence imaging.
Opt Lett
; 43(20): 5162-5165, 2018 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30320845
8.
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Bioorg Med Chem Lett
; 28(23-24): 3721-3725, 2018 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30348490
9.
Pupil segmentation adaptive optics for invivo mouse retinal fluorescence imaging.
Opt Lett
; 42(7): 1365-1368, 2017 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28362770
10.
An unanticipated architecture of the 750-kDa α6ß6 holoenzyme of 3-methylcrotonyl-CoA carboxylase.
Nature
; 481(7380): 219-23, 2011 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-22158123
11.
Soil-Transmitted Helminth Infections Are Associated With an Increase in Human Papillomavirus Prevalence and a T-Helper Type 2 Cytokine Signature in Cervical Fluids.
J Infect Dis
; 213(5): 723-30, 2016 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26486638
12.
Ectopic Expression of α6 and δ GABAA Receptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus.
J Neurosci
; 35(49): 16142-58, 2015 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26658866
13.
Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase.
Nature
; 466(7309): 1001-5, 2010 Aug 19.
Artigo
Inglês
| MEDLINE | ID: mdl-20725044
14.
Pseudosaccharin amines as potent and selective KV1.5 blockers.
Bioorg Med Chem Lett
; 25(21): 4983-4986, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25801931
15.
Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies.
Bioorg Med Chem Lett
; 25(20): 4412-8, 2015 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26386604
16.
Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup.
Bioorg Med Chem Lett
; 25(14): 2793-9, 2015 Jul 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26022839
17.
A reorganized GABAergic circuit in a model of epilepsy: evidence from optogenetic labeling and stimulation of somatostatin interneurons.
J Neurosci
; 33(36): 14392-405, 2013 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-24005292
18.
2-Amino-1,3,4-thiadiazoles in the 7-hydroxy-N-neopentyl spiropiperidine indolinyl series as potent P2Y1 receptor antagonists.
Bioorg Med Chem Lett
; 24(11): 2481-5, 2014 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24767843
19.
Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors.
Bioorg Med Chem Lett
; 24(3): 860-4, 2014 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24424134
20.
Identification of 1-{2-[4-chloro-1'-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y(1) antagonist as an antiplatelet agent.
Bioorg Med Chem Lett
; 24(5): 1294-8, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24513044