Detalhe da pesquisa
1.
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling.
Nat Immunol
; 12(5): 408-15, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21478880
2.
Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis.
J Biol Chem
; 287(39): 32791-9, 2012 Sep 21.
Artigo
Inglês
| MEDLINE | ID: mdl-22843689
3.
The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome.
J Biol Chem
; 286(22): 19605-16, 2011 Jun 03.
Artigo
Inglês
| MEDLINE | ID: mdl-21487011
4.
Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis.
J Immunol
; 185(9): 5476-85, 2010 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20921527
5.
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.
J Immunol
; 182(10): 6460-9, 2009 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19414800
6.
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.
J Immunol
; 183(3): 2008-15, 2009 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19587006
7.
Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells.
J Immunol
; 182(4): 2395-404, 2009 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19201894
8.
Short hairpin RNA (shRNA): design, delivery, and assessment of gene knockdown.
Methods Mol Biol
; 629: 141-58, 2010.
Artigo
Inglês
| MEDLINE | ID: mdl-20387148