Detalhe da pesquisa
1.
Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs.
Nat Immunol
; 21(5): 535-545, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32313245
2.
Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML.
Blood
; 142(11): 989-1007, 2023 09 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37172199
3.
Inactivation of p53 provides a competitive advantage to del(5q) myelodysplastic syndrome hematopoietic stem cells during inflammation.
Haematologica
; 108(10): 2715-2729, 2023 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37102608
4.
Dysregulated innate immune signaling cooperates with RUNX1 mutations to transform an MDS-like disease to AML.
iScience
; 27(6): 109809, 2024 Jun 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38784013
5.
The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia.
Leukemia
; 36(2): 438-451, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34465865
6.
TRAF6 functions as a tumor suppressor in myeloid malignancies by directly targeting MYC oncogenic activity.
Cell Stem Cell
; 29(2): 298-314.e9, 2022 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35045331
7.
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia.
Sci Transl Med
; 14(635): eabb7695, 2022 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35263148
8.
TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Cell Rep
; 36(2): 109386, 2021 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34260914
9.
Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia.
Cell Stem Cell
; 28(11): 1966-1981.e6, 2021 11 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34473945
10.
TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis.
Cell Rep
; 30(8): 2776-2790.e6, 2020 02 25.
Artigo
Inglês
| MEDLINE | ID: mdl-32101751
11.
Targeting AML-associated FLT3 mutations with a type I kinase inhibitor.
J Clin Invest
; 130(4): 2017-2023, 2020 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32149729
12.
Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
Sci Transl Med
; 11(508)2019 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31484791
13.
TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.
Cell Rep
; 22(5): 1250-1262, 2018 01 30.
Artigo
Inglês
| MEDLINE | ID: mdl-29386112