Detalhe da pesquisa
1.
SARS-CoV-2 DNA Vaccine INO-4800 Induces Durable Immune Responses Capable of Being Boosted in a Phase 1 Open-Label Trial.
J Infect Dis
; 225(11): 1923-1932, 2022 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35079784
2.
Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics.
Mol Ther
; 27(1): 188-199, 2019 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30449662
3.
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus.
Mol Ther
; 27(5): 974-985, 2019 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30962164
4.
Synergy of Immune Checkpoint Blockade with a Novel Synthetic Consensus DNA Vaccine Targeting TERT.
Mol Ther
; 26(2): 435-445, 2018 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29249395
5.
Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.
Blood
; 121(9): 1524-33, 2013 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23264589
6.
Patient monitoring and follow-up in lentiviral clinical trials.
J Gene Med
; 15(2): 78-82, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23322669
7.
Delineation of DNA and mRNA COVID-19 vaccine-induced immune responses in preclinical animal models.
Hum Vaccin Immunother
; 19(3): 2281733, 2023 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38012018
8.
Engineered DNA-encoded monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein confer single dose protection in a murine malaria challenge model.
Sci Rep
; 12(1): 14313, 2022 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35995959
9.
Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model.
Hum Vaccin Immunother
; 18(1): 2016201, 2022 12 31.
Artigo
Inglês
| MEDLINE | ID: mdl-35061975
10.
Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo.
Cell Rep Med
; 3(7): 100693, 2022 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35839767
11.
Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates.
Vaccine
; 40(21): 2960-2969, 2022 05 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35428500
12.
Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun
; 13(1): 695, 2022 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35121758
13.
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection.
Cell Rep
; 38(5): 110318, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35090597
14.
Immunotherapy of prostate cancer using novel synthetic DNA vaccines targeting multiple tumor antigens.
Genes Cancer
; 12: 51-64, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33884106
15.
Phase 1 study of safety, tolerability and immunogenicity of the human telomerase (hTERT)-encoded DNA plasmids INO-1400 and INO-1401 with or without IL-12 DNA plasmid INO-9012 in adult patients with solid tumors.
J Immunother Cancer
; 9(7)2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34230114
16.
Multivalent DNA Vaccines as A Strategy to Combat Multiple Concurrent Epidemics: Mosquito-Borne and Hemorrhagic Fever Viruses.
Viruses
; 13(3)2021 02 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33673603
17.
Identification of Novel Neutralizing Monoclonal Antibodies against SARS-CoV-2 Spike Glycoprotein.
ACS Pharmacol Transl Sci
; 4(4): 1349-1361, 2021 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34396059
18.
Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus.
JCI Insight
; 6(10)2021 05 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33886507
19.
INO-4800 DNA vaccine induces neutralizing antibodies and T cell activity against global SARS-CoV-2 variants.
NPJ Vaccines
; 6(1): 121, 2021 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-34650089
20.
One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model.
Vaccine
; 39(34): 4885-4894, 2021 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34253420