Detalhe da pesquisa
1.
Roadmap for the Emerging Field of Cancer Neuroscience.
Cell
; 181(2): 219-222, 2020 04 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32302564
2.
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.
Cell
; 155(4): 844-57, 2013 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24209622
3.
Targeting metabolic changes in cancer: novel therapeutic approaches.
Annu Rev Med
; 65: 157-70, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24422570
4.
Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry
; 50(50): 10764-70, 2011 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-22049910
5.
GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis.
J Lipid Res
; 51(7): 1971-81, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-20181984
6.
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase.
Mol Cancer Ther
; 19(12): 2502-2515, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33082276
7.
Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity.
Curr Biol
; 14(8): 736-41, 2004 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-15084291
8.
Action at a distance: allostery and the development of drugs to target cancer cell metabolism.
Chem Biol
; 21(9): 1143-61, 2014 Sep 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25237859
9.
Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition.
PLoS One
; 9(12): e115144, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-25502225
10.
Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.
Mol Cell Biol
; 30(21): 5043-56, 2010 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-20733003
11.
The Par-1/MARK family of protein kinases: from polarity to metabolism.
Cell Cycle
; 6(16): 1966-9, 2007 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17721078
12.
Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo.
Proc Natl Acad Sci U S A
; 104(13): 5680-5, 2007 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-17372192
13.
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.
Blood
; 107(10): 3868-75, 2006 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16434494