Detalhe da pesquisa
1.
Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.
Cell
; 172(5): 952-965.e18, 2018 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29474921
2.
mTOR Attenuation with Rapamycin Reverses Neurovascular Uncoupling and Memory Deficits in Mice Modeling Alzheimer's Disease.
J Neurosci
; 41(19): 4305-4320, 2021 05 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33888602
3.
Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer's disease and vascular cognitive impairment.
Am J Physiol Heart Circ Physiol
; 314(4): H693-H703, 2018 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29351469
4.
Retinal dendritic cell recruitment, but not function, was inhibited in MyD88 and TRIF deficient mice.
J Neuroinflammation
; 11: 143, 2014 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-25116321
5.
Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.
J Neurochem
; 124(6): 880-93, 2013 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-23121022
6.
Rapamycin restores peripheral blood flow in aged mice and in mouse models of atherosclerosis and Alzheimer's disease.
Geroscience
; 45(3): 1987-1996, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37052770
7.
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy.
Nat Commun
; 14(1): 2367, 2023 04 25.
Artigo
Inglês
| MEDLINE | ID: mdl-37185259
8.
Primary neuron and astrocyte cultures from postnatal Callithrix jacchus: a non-human primate in vitro model for research in neuroscience, nervous system aging, and neurological diseases of aging.
Geroscience
; 43(1): 115-124, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33063253
9.
Immunoproteasome deficiency alters retinal proteasome's response to stress.
J Neurochem
; 113(6): 1481-90, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20345760
10.
mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging.
Aging Cell
; 19(1): e13057, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31693798
11.
Immunoproteasome responds to injury in the retina and brain.
J Neurochem
; 106(1): 158-69, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-18346202
12.
mTOR drives cerebral blood flow and memory deficits in LDLR-/- mice modeling atherosclerosis and vascular cognitive impairment.
J Cereb Blood Flow Metab
; 38(1): 58-74, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28511572
13.
Transformation of the proteasome with age-related macular degeneration.
FEBS Lett
; 581(5): 885-90, 2007 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-17289037
14.
Correction to: Primary neuron and astrocyte cultures from postnatal Callithrix jacchus: a non-human primate in vitro model for research in neuroscience, nervous system aging, and neurological diseases of aging.
Geroscience
; 44(2): 1171, 2022 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-35107706
15.
Immunoproteasome deficiency protects in the retina after optic nerve crush.
PLoS One
; 10(5): e0126768, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25978061
16.
Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.
J Cereb Blood Flow Metab
; 33(9): 1412-21, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23801246
17.
Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.
J Cereb Blood Flow Metab
; 33(10): 1605-11, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23838831
18.
A novel role for the immunoproteasome in retinal function.
Invest Ophthalmol Vis Sci
; 52(2): 714-23, 2011 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20881299
19.
A new mouse model to study compensatory mechanisms that support normal motor function in Parkinson's disease.
J Biochem Pharmacol Res
; 2(2): 54-56, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-26405617