Detalhe da pesquisa
1.
Using the Dynamic Well-Stirred Model to Extrapolate Hepatic Clearance of Organic Anion-Transporting Polypeptide Transporter Substrates without Assuming Albumin-Mediated Hepatic Drug Uptake.
Drug Metab Dispos
; 52(6): 548-554, 2024 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38604729
2.
"PROTAC" modified dihydroquinolizinones (DHQs) that cause degradation of PAPD-5 and inhibition of hepatitis A virus and hepatitis B virus, in vitro.
Bioorg Med Chem Lett
; 102: 129680, 2024 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38428537
3.
4-Oxooctahydroquinoline-1(2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators.
Bioorg Med Chem Lett
; 58: 128518, 2022 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34979256
4.
Synthesis of 4-oxotetrahydropyrimidine-1(2H)-carboxamides derivatives as capsid assembly modulators of hepatitis B virus.
Med Chem Res
; 30(2): 459-472, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33456291
5.
Identification of a 3-ß-homoalanine conjugate of brusatol with reduced toxicity in mice.
Bioorg Med Chem Lett
; 30(23): 127553, 2020 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32971261
6.
Discovery and Mechanistic Study of Benzamide Derivatives That Modulate Hepatitis B Virus Capsid Assembly.
J Virol
; 91(16)2017 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28566379
7.
Introducing the Dynamic Well-Stirred Model for Predicting Hepatic Clearance and Extraction Ratio.
J Pharm Sci
; 113(4): 1094-1112, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38220087
8.
Identification of novel tetrahydroquinoxaline derived phenyl ureas as modulators of the hepatitis B virus nucleocapsid assembly.
Eur J Med Chem
; 259: 115634, 2023 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37499290
9.
Hepatoselective Dihydroquinolizinone Bis-acids for HBsAg mRNA Degradation.
ACS Med Chem Lett
; 12(7): 1130-1136, 2021 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34267883
10.
Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators.
Antiviral Res
; 191: 105080, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-33933516
11.
Quassinoid analogs with enhanced efficacy for treatment of hematologic malignancies target the PI3Kγ isoform.
Commun Biol
; 3(1): 267, 2020 05 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32461675
12.
Discovery of Novel Hepatitis B Virus Nucleocapsid Assembly Inhibitors.
ACS Infect Dis
; 5(5): 759-768, 2019 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30525438
13.
Discovery and Mechanistic Study of a Novel Human-Stimulator-of-Interferon-Genes Agonist.
ACS Infect Dis
; 5(7): 1139-1149, 2019 07 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31060350
14.
Colloidal Covalent Organic Frameworks.
ACS Cent Sci
; 3(1): 58-65, 2017 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28149954
15.
Insight into the crystallization of amorphous imine-linked polymer networks to 2D covalent organic frameworks.
Chem Commun (Camb)
; 52(18): 3690-3, 2016 Mar 04.
Artigo
Inglês
| MEDLINE | ID: mdl-26857035
16.
Growth rates and water stability of 2D boronate ester covalent organic frameworks.
Chem Commun (Camb)
; 51(35): 7532-5, 2015 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25848654