Detalhe da pesquisa
1.
Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides.
Nucleic Acids Res
; 51(10): 4713-4725, 2023 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37099382
2.
Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis.
Nature
; 563(7730): 235-240, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30356213
3.
Brave new surfactant world revisited by thermoalkalophilic lipases: computational insights into the role of SDS as a substrate analog.
Phys Chem Chem Phys
; 25(3): 2234-2247, 2023 Jan 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36594810
4.
Enzyme Conformation Influences the Performance of Lipase-powered Nanomotors.
Angew Chem Int Ed Engl
; 59(47): 21080-21087, 2020 11 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32755070
5.
Deciphering the Allosterically Driven Conformational Ensemble in Tryptophan Synthase Evolution.
J Am Chem Soc
; 141(33): 13049-13056, 2019 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31356074
6.
Multivalent Ligands with Tailor-Made Anion Binding Motif as Stabilizers of Protein-Protein Interactions.
Chembiochem
; 20(23): 2921-2926, 2019 12 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31168888
7.
A front-face 'SNi synthase' engineered from a retaining 'double-SN2' hydrolase.
Nat Chem Biol
; 13(8): 874-881, 2017 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-28604696
8.
Hidden Conformations in Aspergillus niger Monoamine Oxidase are Key for Catalytic Efficiency.
Angew Chem Int Ed Engl
; 58(10): 3097-3101, 2019 03 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30600584
9.
A Multiperspective Approach to Solvent Regulation of Enzymatic Activity: HMG-CoA Reductase.
Chembiochem
; 19(2): 153-158, 2018 01 18.
Artigo
Inglês
| MEDLINE | ID: mdl-29139594
10.
Membrane Phase-Dependent Occlusion of Intramolecular GLUT1 Cavities Demonstrated by Simulations.
Biophys J
; 112(6): 1176-1184, 2017 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28355545
11.
The reaction mechanism of retaining glycosyltransferases.
Biochem Soc Trans
; 44(1): 51-60, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26862188
12.
Surfactin at the Water/Air Interface and in Solution.
Langmuir
; 31(40): 11097-104, 2015 Oct 13.
Artigo
Inglês
| MEDLINE | ID: mdl-26393968
13.
Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism.
Angew Chem Int Ed Engl
; 54(18): 5378-82, 2015 Apr 27.
Artigo
Inglês
| MEDLINE | ID: mdl-25772148
14.
Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate.
Angew Chem Int Ed Engl
; 53(4): 1087-91, 2014 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-24339341
15.
Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferaseâ 2.
Angew Chem Int Ed Engl
; 53(31): 8206-10, 2014 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-24954443
16.
Nucleic acids in modern molecular therapies: A realm of opportunities for strategic drug design.
Curr Opin Struct Biol
; 87: 102838, 2024 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38759298
17.
Structural analysis and insights into the glycon specificity of the rice GH1 Os7BGlu26 ß-D-mannosidase.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 10): 2124-35, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-24100330
18.
MEP pathway products allosterically promote monomerization of deoxy-D-xylulose-5-phosphate synthase to feedback-regulate their supply.
Plant Commun
; 4(3): 100512, 2023 05 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36575800
19.
Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α.
Nat Commun
; 14(1): 7920, 2023 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38040726
20.
Designing Efficient Enzymes: Eight Predicted Mutations Convert a Hydroxynitrile Lyase into an Efficient Esterase.
bioRxiv
; 2023 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37662272