Detalhe da pesquisa
1.
Preclinical evaluation of general toxicity and safety pharmacology of a receptor-binding domain-based COVID-19 subunit vaccine in various animal models.
Arch Toxicol
; 97(9): 2429-2440, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37491472
2.
Preclinical safety assessment of a therapeutic human papillomavirus DNA vaccine combined with intravaginal interleukin-7 fused with hybrid Fc in female rats.
Toxicol Appl Pharmacol
; 413: 115406, 2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33434572
3.
In vitro skin irritation assessment using EpiDerm™: applicability for updating toxicity information of oxybenzone and N,N-diethyl-m-toluamide.
Drug Chem Toxicol
; 43(4): 361-368, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-31305169
4.
Reproductive and developmental toxicity screening of polyhexamethylene guanidine phosphate by oral gavage in rats.
Regul Toxicol Pharmacol
; 108: 104440, 2019 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-31398363
5.
Long-chain perfluoroalkyl carboxylates induce cytoskeletal abnormalities and activate epithelial-mesenchymal transition in both renal cell carcinoma 3D cultures and Caki-1 xenografted mouse model.
Environ Int
; 178: 108093, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37459689
6.
Two weeks dose range-finding and four weeks repeated dose oral toxicity study of a novel reversible monoamine oxidase B inhibitor KDS2010 in cynomolgus monkeys.
Toxicol Res
; 39(4): 693-709, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37779583
7.
Safety assessment of cerium oxide nanoparticles: combined repeated-dose toxicity with reproductive/developmental toxicity screening and biodistribution in rats.
Nanotoxicology
; 14(5): 696-710, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32301357
8.
Higher incidence of sperm granuloma in the epididymis of C57BL/6N mice.
Lab Anim Res
; 34(1): 20-29, 2018 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-29628973
9.
Reference values of clinical pathology parameters in cynomolgus monkeys (Macaca fascicularis) used in preclinical studies.
Lab Anim Res
; 32(2): 79-86, 2016 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-27382375