TWO NEW SINGLE-EXPOSURE, MULTI-DETECTOR NEUTRON SPECTROMETERS FOR RADIATION PROTECTION APPLICATIONS IN WORKPLACE MONITORING.

This communication describes two new instruments, based on multiple active thermal neutron detectors arranged within a single moderator, that permit to unfold the neutron spectrum (from thermal to hundreds of MeV) and to determine the corresponding integral quantities with only one exposure. This makes them especially advantageous for neutron field characterisation and workplace monitoring in neutron-producing facilities. One of the devices has spherical geometry and nearly isotropic response, the other one has cylindrical symmetry and it is only sensitive to neutrons incident along the cylinder axis. In both cases, active detectors have been specifically developed looking for the criteria of miniaturisation, high sensitivity, linear response and good photon rejection. The calculated response matrix has been validated by experimental irradiations in neutron reference fields with a global uncertainty of 3%. The measurements performed in realistic neutron fields permitted to determine the neutron spectra and the integral quantities, in particular H*(10).

ETHERNES: A new design of radionuclide source-based thermal neutron facility with large homogeneity area.

A new thermal neutron irradiation facility based on an (241)Am-Be source embedded in a polyethylene moderator has been designed, and is called ETHERNES (Extended THERmal NEutron Source). The facility shows a large irradiation cavity (45 cm × 45 cm square section, 63 cm in height), which is separated from the source by means of a polyethylene sphere acting as shadowing object. Taking advantage of multiple scattering of neutrons with the walls of this cavity, the moderation process is especially effective and allows obtaining useful thermal fluence rates from 550 to 800 cm(-2) s(-1) with a source having nominal emission rate 5.7×10(6) s(-1). Irradiation planes parallel to the cavity bottom have been identified. The fluence rate across a given plane is as uniform as 3% (or better) in a disk with 30 cm (or higher) diameter. In practice, the value of thermal fluence rate simply depends on the height from the cavity bottom. The thermal neutron spectral fraction ranges from 77% up to 89%, depending on the irradiation plane. The angular distribution of thermal neutrons is roughly isotropic, with a slight prevalence of directions from bottom to top of the cavity. The mentioned characteristics are expected to be attractive for the scientific community involved in neutron metrology, neutron dosimetry and neutron detector testing.

A SINGLE-EXPOSURE, MULTIDETECTOR NEUTRON SPECTROMETER FOR WORKPLACE MONITORING.

This communication describes a recently developed single-exposure neutron spectrometer, based on multiple active thermal neutron detectors located within a moderating sphere, which have been developed jointly by CIEMAT (Spain), INFN (Italy) and Politecnico di Milano (Italy) in the framework of Italian and Spanish collaboration projects. The fabricated prototypes permit to achieve spectrometric resolution with nearly isotropic response for neutron with energies from thermal to 100-200 MeV, thus being able to characterise the complete neutron spectrum in only one exposure by unfolding the measured responses of the detectors. This makes it especially advantageous for characterising neutron fields and workplace monitoring purposes in neutron-producing facilities.

A new active thermal neutron detector.

This communication presents the main results about the design and in-house fabrication of a new solid-state neutron detector, which produces a DC output signal proportional to the thermal neutron fluence rate. The detector has been developed within the framework of the 3-y project NESCOFI@BTF of INFN (CSN V). Due to its sensitivity, photon rejection, low cost and minimum size, this device is suited to be used in moderator-based spectrometers.

Development of single-exposure, multidetector neutron spectrometers: the NESCOFI@BTF project.

NESCOFI@BTF is a 3-y project (2011-13) supported by the Scientific Commission 5 of INFN (Italy). The target is the development of neutron spectrometers similar to the Bonner spheres, in terms of response energy interval and accuracy, but able to determine the neutron spectrum in only one exposure. These devices embed multiple (10 to 30) thermal neutron detectors (TNDs) within a single moderator. Two prototypes, called SPherical SPectrometer (SP(2)) and cylindrical spectrometer (CYSP), have been set up. Whilst SP(2) has spherical geometry and nearly isotropic response, the CYSP has cylindrical geometry and is intended to be used as a directional spectrometer. Suitable active TNDs will be embedded in the final version of the devices. The resulting instruments could be used as real-time neutron spectrometers in neutron-producing facilities. This communication describes the design criteria, numerical analysis, experimental issues, state-of-the-art and future developments connected with the development of these instruments.

Compact thermal neutron sensors for moderator-based neutron spectrometers.

In the framework of the NESCOFI@BTF project of the Italian Institute of Nuclear Physics, different types of active thermal neutron sensors were studied by coupling semiconductor devices with a suitable radiator. The objective was to develop a detector of small dimensions with a proper sensitivity to use at different positions in a novel moderating assembly for neutron spectrometry. This work discusses the experimental activity carried out in the framework of the ERINDA program (PAC 3/9 2012) to characterise the performance of a thermal neutron pulse detector based on (6)Li.

Characterization of the energy distribution of neutrons generated by 5 MeV protons on a thick beryllium target at different emission angles.

Neutron energy spectra at different emission angles, between 0° and 120° from the Be(p,xn) reaction generated by a beryllium thick-target bombarded with 5 MeV protons, have been measured at the Legnaro Laboratories (LNL) of the Italian National Institute for Nuclear Physics research (INFN). A new and quite compact recoil-proton spectrometer, based on a monolithic silicon telescope, coupled to a polyethylene converter, was efficiently used with respect to the traditional Time-of-Flight (TOF) technique. The measured distributions of recoil-protons were processed through an iterative unfolding algorithm in order to determine the neutron energy spectra at all the angles accounted for. The neutron energy spectrum measured at 0° resulted to be in good agreement with the only one so far available at the requested energy and measured years ago with TOF technique. Moreover, the results obtained at different emission angles resulted to be consistent with detailed past measurements performed at 4 MeV protons at the same angles by TOF techniques.

Study of a solid state microdosemeter based on a monolithic silicon telescope: irradiations with low-energy neutrons and direct comparison with a cylindrical TEPC.

A silicon device based on the monolithic silicon telescope technology coupled to a tissue-equivalent converter was proposed and investigated for solid state microdosimetry. The detector is constituted by a ΔE stage about 2 µm in thickness geometrically segmented in a matrix of micrometric diodes and a residual-energy measurement stage E about 500 µm in thickness. Each thin diode has a cylindrical sensitive volume 9 µm in nominal diameter, similar to that of a cylindrical tissue-equivalent proportional counter (TEPC). The silicon device and a cylindrical TEPC were irradiated in the same experimental conditions with quasi-monoenergetic neutrons of energy between 0.64 and 2.3 MeV at the INFN-Legnaro National Laboratories (LNL-INFN, Legnaro, Italy). The aim was to study the capability of the silicon-based system of reproducing microdosimetric spectra similar to those measured by a reference microdosemeter. The TEPC was set in order to simulate a tissue site about 2 µm in diameter. The spectra of the energy imparted to the ▵E stage of the silicon telescope were corrected for tissue-equivalence through an optimized procedure that exploits the information from the residual energy measurement stage E. A geometrical correction based on parametric criteria for shape-equivalence was also applied. The agreement between the dose distributions of lineal energy and the corresponding mean values is satisfactory at each neutron energy considered.

[Experimental Chagas' disease: I. Study of different immunization conditions in the infection course]. / Enfermedad de Chagas experimental: I. Estudio de diferentes condiciones de inmunización sobre el curso de la infección.

In previous works it has been demonstrated that Balb/c albino mice immunized with Trypanosoma rangeli developed cellular and humoral immune response to Tripanosoma cruzi. Moreover, the immunized animals were protected against lethal infection by virulent T. cruzi trypomastigotes. In fact, immunized mice had significantly lower parasitemias and longer survival than controls. To go further in this experimental model, the aim of the present work was to analyze the effect of the number of antigenic stimuli and the conservation of the antigen on the effectiveness of protective effect. For that purpose, three different immunization schedules injecting T. rangeli epimastigotes fixed with glutaraldehide and emulsified with Saponin (SAP) as adjuvant were assayed. Different lots of mice which received only phosphate buffer saline or SAP were used as controls. In another set of experiments the conservation of the antigen during 90 days at 4 degrees C was studied. In all the experiments mice were infected with 100 trypomastigotes of T. cruzi, Tulahuén strain. The parasitemias were analyzed on 13th, 16th and 21st post infection days, and the survival until the 60th day. The results revealed that one dose of antigen was inadequate to give an effective protection. On the other hand, mice immunized with 2 and 3 dose showed a significant decrease of parasitemia with regard to controls (p < 0.001 - p < 0.0001) and the survival were markedly increased. Likewise, the antigen kept during 90th days at 4 degrees C showed similar protective efficacy than fresh antigen. Both of these experimental groups showed significant differences with respect to control animals in parasitemia (p < 0.05 - p > 0.01) and survival (p < 0.01). In conclusion, the results of this work showed that in the experimental conditions assayed, the immunization with T. rangeli trigger and adequate immune response when mice received at least two antigenic stimuli. Likewise, it is interesting to point out the stability of the antigenic preparation during at least 90th days.