Social appearance anxiety, emotional regulation and quality of life in individuals with premature canities: A correlational study.

OBJECTIVE: To examine and predict the relationship among social appearance anxiety, emotional regulation and quality of life in individuals with premature canities. METHODS: The correlational study was conducted from September 2019 to February 2020 in Lahore, Pakistan, after approval from the Riphah International University, Lahore, and comprised individuals of either gender aged 15-25 years with premature canities. Social Appearance Anxiety Scale, Emotional Regulation Questionnaire and the Quality of Life Scale were used to measure the study variables. Data was analysed using SPSS 21. RESULTS: Of the 100 subjects, 50(50%) each were males and females. The overall mean age was 19.80±3.33 years. Individuals with premature canities had significant social appearance anxiety which was positively correlated with emotional suppression. As social appearance anxiety increased, the quality of life decreased (p<0.05). Lower level of cognitive reappraisal and higher expressive suppression were linked with improved quality of life in individuals with premature canities (p<0.05). CONCLUSIONS: Social appearance anxiety, emotional regulation along with age were together found to be the predictors of quality of life.

Dark triad, risk propensity and interpersonal relationship satisfaction in clients with substance use disorder.

OBJECTIVE: To examine the relationship of drug addicts with personality triad, risk propensity and interpersonal relationship satisfaction. METHODS: The correlational study was conducted from September 2019 to February 2020 in different hospitals of Lahore, Pakistan, and comprised male drug addicts aged 18-30 years. Data was collected using the Dark Triad of Personalityscale, the Risk Propensity Scale and the Interpersonal Relationship Satisfaction Scale. Data was analysed using SPSS 21. RESULTS: There were 100 men with a mean age of 25.03±3.82 years. CONCLUSIONS: Dark triad and risk propensity significantly predicted interpersonal relationship satisfaction, while narcissism did not predict interpersonal relationship satisfaction.

Effects of colchicine on pericardial diseases: a review of the literature and current evidence.

Colchicine, extracted from the colchicum autumnale plant, used by the ancient Greeks more than 20 centuries ago, is one of the most ancient drugs still prescribed even today. The major mechanism of action is binding to microtubules thereby interfering with mitosis and subsequent modulation of polymorphonuclear leukocyte function. Colchicine has long been of interest in the treatment of cardiovascular disease; however, its efficacy and safety profile for specific conditions have been variably established in the literature. In the subset of pericardial diseases, colchicine has been shown to be effective in recurrent pericarditis and post-pericardiotomy syndrome (PPS). The future course of treatment and management will therefore highly depend on the results of the ongoing large randomized placebo-controlled clinical trial to evaluate the efficacy and safety of colchicine for the primary prevention of several postoperative complications and in the perioperative period. Also, given the positive preliminary outcomes of colchicine usage in pericardial effusions, the future therapeutical use of colchicine looks promising. Further study is needed to clarify its role in these disease states, as well as explore other its role in other cardiovascular conditions.