Detalhe da pesquisa
1.
The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of ß Cells.
PLoS Biol
; 13(10): e1002277, 2015 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26469762
2.
Tolerance of human embryonic stem cell derived islet progenitor cells to vitrification-relevant solutions.
Cryobiology
; 70(3): 283-6, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25817378
3.
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Protein Sci
; 33(4): e4949, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38511500
4.
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.
Nat Med
; 12(3): 310-6, 2006 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-16491084
5.
Cryopreservation of human insulin expressing cells macro-encapsulated in a durable therapeutic immunoisolating device theracyte.
Cryo Letters
; 33(6): 518-31, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-23250411
6.
Expression Profiles of ID and E2A in Ovarian Cancer and Suppression of Ovarian Cancer by the E2A Isoform E47.
Cancers (Basel)
; 14(12)2022 Jun 12.
Artigo
Inglês
| MEDLINE | ID: mdl-35740568
7.
Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
J Clin Endocrinol Metab
; 107(11): 3100-3110, 2022 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36017587
8.
Normal and defective pathways in biogenesis and maintenance of the insulin storage pool.
J Clin Invest
; 131(2)2021 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33463547
9.
Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
Diabetes
; 69(8): 1723-1734, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32457219
10.
Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth.
Diabetes
; 69(5): 954-964, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32139596
11.
beta-cell Regeneration: neogenesis, replication or both?
J Mol Med (Berl)
; 86(3): 247-58, 2008 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-17922102
12.
Proinsulin misfolding is an early event in the progression to type 2 diabetes.
Elife
; 82019 06 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31184302
13.
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Elife
; 82019 06 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31184304
14.
Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment.
Mol Oncol
; 12(7): 1104-1124, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29719936
15.
E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53.
Cell Mol Gastroenterol Hepatol
; 6(2): 181-198, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30003124
16.
A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer.
Oncotarget
; 8(32): 53154-53167, 2017 Aug 08.
Artigo
Inglês
| MEDLINE | ID: mdl-28881801
17.
When Less Is Better: ER Stress and Beta Cell Proliferation.
Dev Cell
; 36(1): 4-6, 2016 Jan 11.
Artigo
Inglês
| MEDLINE | ID: mdl-26766438
18.
The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.
Pancreas
; 44(5): 718-27, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25894862
19.
c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells.
J Clin Endocrinol Metab
; 87(7): 3475-85, 2002 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-12107268
20.
Cell-based therapies for diabetes: progress towards a transplantable human beta cell line.
Ann N Y Acad Sci
; 1005: 138-47, 2003 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-14679048