Pesquisa | Secretaria de Estado da Saúde

1.

SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.

Wu, Chien-Ting; Lidsky, Peter V; Xiao, Yinghong; Cheng, Ran; Lee, Ivan T; Nakayama, Tsuguhisa; Jiang, Sizun; He, Wei; Demeter, Janos; Knight, Miguel G; Turn, Rachel E; Rojas-Hernandez, Laura S; Ye, Chengjin; Chiem, Kevin; Shon, Judy; Martinez-Sobrido, Luis; Bertozzi, Carolyn R; Nolan, Garry P; Nayak, Jayakar V; Milla, Carlos; Andino, Raul; Jackson, Peter K.

Cell ; 186(1): 112-130.e20, 2023 01 05.

Artigo Inglês | MEDLINE | ID: mdl-36580912

2.

A defective viral genome strategy elicits broad protective immunity against respiratory viruses.

Xiao, Yinghong; Lidsky, Peter V; Shirogane, Yuta; Aviner, Ranen; Wu, Chien-Ting; Li, Weiyi; Zheng, Weihao; Talbot, Dale; Catching, Adam; Doitsh, Gilad; Su, Weiheng; Gekko, Colby E; Nayak, Arabinda; Ernst, Joel D; Brodsky, Leonid; Brodsky, Elia; Rousseau, Elsa; Capponi, Sara; Bianco, Simone; Nakamura, Robert; Jackson, Peter K; Frydman, Judith; Andino, Raul.

Cell ; 184(25): 6037-6051.e14, 2021 12 09.

Artigo Inglês | MEDLINE | ID: mdl-34852237

3.

cAMP Signaling in Nanodomains.

Jackson, Peter K.

Cell ; 182(6): 1379-1381, 2020 09 17.

Artigo Inglês | MEDLINE | ID: mdl-32946779

4.

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.

Hilgendorf, Keren I; Johnson, Carl T; Mezger, Anja; Rice, Selena L; Norris, Alessandra M; Demeter, Janos; Greenleaf, William J; Reiter, Jeremy F; Kopinke, Daniel; Jackson, Peter K.

Cell ; 179(6): 1289-1305.e21, 2019 11 27.

Artigo Inglês | MEDLINE | ID: mdl-31761534

5.

Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma.

Qin, Elizabeth Y; Cooper, Dominique D; Abbott, Keene L; Lennon, James; Nagaraja, Surya; Mackay, Alan; Jones, Chris; Vogel, Hannes; Jackson, Peter K; Monje, Michelle.

Cell ; 170(5): 845-859.e19, 2017 Aug 24.

Artigo Inglês | MEDLINE | ID: mdl-28823557

6.

Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation.

Janas, Justyna A; Zhang, Lichao; Luu, Jacklyn H; Demeter, Janos; Meng, Lingjun; Marro, Samuele G; Mall, Moritz; Mooney, Nancie A; Schaukowitch, Katie; Ng, Yi Han; Yang, Nan; Huang, Yuhao; Neumayer, Gernot; Gozani, Or; Elias, Joshua E; Jackson, Peter K; Wernig, Marius.

Mol Cell ; 82(24): 4627-4646.e14, 2022 12 15.

Artigo Inglês | MEDLINE | ID: mdl-36417913

7.

The Mettl3 epitranscriptomic writer amplifies p53 stress responses.

Raj, Nitin; Wang, Mengxiong; Seoane, Jose A; Zhao, Richard L; Kaiser, Alyssa M; Moonie, Nancie A; Demeter, Janos; Boutelle, Anthony M; Kerr, Craig H; Mulligan, Abigail S; Moffatt, Clare; Zeng, Shelya X; Lu, Hua; Barna, Maria; Curtis, Christina; Chang, Howard Y; Jackson, Peter K; Attardi, Laura D.

Mol Cell ; 82(13): 2370-2384.e10, 2022 07 07.

Artigo Inglês | MEDLINE | ID: mdl-35512709

8.

Structured elements drive extensive circular RNA translation.

Chen, Chun-Kan; Cheng, Ran; Demeter, Janos; Chen, Jin; Weingarten-Gabbay, Shira; Jiang, Lihua; Snyder, Michael P; Weissman, Jonathan S; Segal, Eran; Jackson, Peter K; Chang, Howard Y.

Mol Cell ; 81(20): 4300-4318.e13, 2021 10 21.

Artigo Inglês | MEDLINE | ID: mdl-34437836

9.

Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion.

Wu, Chien-Ting; Hilgendorf, Keren I; Bevacqua, Romina J; Hang, Yan; Demeter, Janos; Kim, Seung K; Jackson, Peter K.

Genes Dev ; 35(17-18): 1243-1255, 2021 09 01.

Artigo Inglês | MEDLINE | ID: mdl-34385262

10.

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.

Mukhopadhyay, Saikat; Wen, Xiaohui; Ratti, Navneet; Loktev, Alexander; Rangell, Linda; Scales, Suzie J; Jackson, Peter K.

Cell ; 152(1-2): 210-23, 2013 Jan 17.

Artigo Inglês | MEDLINE | ID: mdl-23332756

11.

The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport.

Boegholm, Niels; Petriman, Narcis A; Loureiro-López, Marta; Wang, Jiaolong; Vela, Miren Itxaso Santiago; Liu, Beibei; Kanie, Tomoharu; Ng, Roy; Jackson, Peter K; Andersen, Jens S; Lorentzen, Esben.

EMBO J ; 42(18): e111807, 2023 09 18.

Artigo Inglês | MEDLINE | ID: mdl-37606072

12.

TTBK2 kinase: linking primary cilia and cerebellar ataxias.

Jackson, Peter K.

Cell ; 151(4): 697-699, 2012 Nov 09.

Artigo Inglês | MEDLINE | ID: mdl-23141531

13.

The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.

Chaikovsky, Andrea C; Li, Chuan; Jeng, Edwin E; Loebell, Samuel; Lee, Myung Chang; Murray, Christopher W; Cheng, Ran; Demeter, Janos; Swaney, Danielle L; Chen, Si-Han; Newton, Billy W; Johnson, Jeffrey R; Drainas, Alexandros P; Shue, Yan Ting; Seoane, Jose A; Srinivasan, Preethi; He, Andy; Yoshida, Akihiro; Hipkins, Susan Q; McCrea, Edel; Poltorack, Carson D; Krogan, Nevan J; Diehl, J Alan; Kong, Christina; Jackson, Peter K; Curtis, Christina; Petrov, Dmitri A; Bassik, Michael C; Winslow, Monte M; Sage, Julien.

Nature ; 592(7856): 794-798, 2021 04.

Artigo Inglês | MEDLINE | ID: mdl-33854239

14.

The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly.

Torres, Jorge Z; Summers, Matthew K; Peterson, David; Brauer, Matthew J; Lee, James; Senese, Silvia; Gholkar, Ankur A; Lo, Yu-Chen; Lei, Xingye; Jung, Kenneth; Anderson, David C; Davis, David P; Belmont, Lisa; Jackson, Peter K.

Cell ; 147(6): 1309-23, 2011 Dec 09.

Artigo Inglês | MEDLINE | ID: mdl-22153075

15.

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

Sang, Liyun; Miller, Julie J; Corbit, Kevin C; Giles, Rachel H; Brauer, Matthew J; Otto, Edgar A; Baye, Lisa M; Wen, Xiaohui; Scales, Suzie J; Kwong, Mandy; Huntzicker, Erik G; Sfakianos, Mindan K; Sandoval, Wendy; Bazan, J Fernando; Kulkarni, Priya; Garcia-Gonzalo, Francesc R; Seol, Allen D; O'Toole, John F; Held, Susanne; Reutter, Heiko M; Lane, William S; Rafiq, Muhammad Arshad; Noor, Abdul; Ansar, Muhammad; Devi, Akella Radha Rama; Sheffield, Val C; Slusarski, Diane C; Vincent, John B; Doherty, Daniel A; Hildebrandt, Friedhelm; Reiter, Jeremy F; Jackson, Peter K.

Cell ; 145(4): 513-28, 2011 May 13.

Artigo Inglês | MEDLINE | ID: mdl-21565611

16.

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.

Han, Kyuho; Pierce, Sarah E; Li, Amy; Spees, Kaitlyn; Anderson, Gray R; Seoane, Jose A; Lo, Yuan-Hung; Dubreuil, Michael; Olivas, Micah; Kamber, Roarke A; Wainberg, Michael; Kostyrko, Kaja; Kelly, Marcus R; Yousefi, Maryam; Simpkins, Scott W; Yao, David; Lee, Keonil; Kuo, Calvin J; Jackson, Peter K; Sweet-Cordero, Alejandro; Kundaje, Anshul; Gentles, Andrew J; Curtis, Christina; Winslow, Monte M; Bassik, Michael C.

Nature ; 580(7801): 136-141, 2020 04.

Artigo Inglês | MEDLINE | ID: mdl-32238925

17.

Navigating the deubiquitinating proteome with a CompPASS.

Jackson, Peter K.

Cell ; 138(2): 222-4, 2009 Jul 23.

Artigo Inglês | MEDLINE | ID: mdl-19632171

18.

Ethacridine inhibits SARS-CoV-2 by inactivating viral particles.

Li, Xiaoquan; Lidsky, Peter V; Xiao, Yinghong; Wu, Chien-Ting; Garcia-Knight, Miguel; Yang, Junjiao; Nakayama, Tsuguhisa; Nayak, Jayakar V; Jackson, Peter K; Andino, Raul; Shu, Xiaokun.

PLoS Pathog ; 17(9): e1009898, 2021 09.

Artigo Inglês | MEDLINE | ID: mdl-34478458

19.

Connecting autoimmune disease to Bardet-Biedl syndrome and primary cilia.

Kanie, Tomoharu; Jackson, Peter K.

EMBO Rep ; 22(2): e52180, 2021 02 03.

Artigo Inglês | MEDLINE | ID: mdl-33511755

20.

The hunt for cyclin.

Jackson, Peter K.

Cell ; 134(2): 199-202, 2008 Jul 25.

Artigo Inglês | MEDLINE | ID: mdl-18662532

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SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming.

A defective viral genome strategy elicits broad protective immunity against respiratory viruses.

cAMP Signaling in Nanodomains.

Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.

Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma.

Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation.

The Mettl3 epitranscriptomic writer amplifies p53 stress responses.

Structured elements drive extensive circular RNA translation.

Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion.

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.

The IFT81-IFT74 complex acts as an unconventional RabL2 GTPase-activating protein during intraflagellar transport.

TTBK2 kinase: linking primary cilia and cerebellar ataxias.

The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.

The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly.

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.

Navigating the deubiquitinating proteome with a CompPASS.

Ethacridine inhibits SARS-CoV-2 by inactivating viral particles.

Connecting autoimmune disease to Bardet-Biedl syndrome and primary cilia.

The hunt for cyclin.