Detalhe da pesquisa
1.
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-ß-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31871094
2.
The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.
Bioorg Med Chem Lett
; 21(11): 3227-31, 2011 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21550237
3.
Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable ß-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes.
J Med Chem
; 64(14): 10155-10166, 2021 07 22.
Artigo
Inglês
| MEDLINE | ID: mdl-34191513
4.
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-ß-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.
J Med Chem
; 63(6): 2789-2801, 2020 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31765155
5.
Identification of TNF-alpha inhibitors from a split-pool library based on a tyrosine-proline peptidomimetic scaffold.
Bioorg Med Chem Lett
; 13(2): 205-8, 2003 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-12482424
6.
Benzobicyclooctanes as novel inhibitors of TNF-alpha signaling.
Bioorg Med Chem Lett
; 12(7): 1093-7, 2002 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-11909725
7.
The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.
ChemMedChem
; 3(10): 1508-15, 2008 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-18729128