Detalhe da pesquisa
1.
Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors.
Bioorg Med Chem Lett
; 81: 129143, 2023 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36669575
2.
Synthesis and P1' SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors.
Bioorg Med Chem Lett
; 26(20): 5051-5057, 2016 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27612545
3.
Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core.
Bioorg Med Chem Lett
; 25(9): 1856-63, 2015 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25845281
4.
Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8.
J Med Chem
; 50(3): 566-84, 2007 Feb 08.
Artigo
Inglês
| MEDLINE | ID: mdl-17266208
5.
Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa-Tissue Factor Complex.
J Med Chem
; 59(15): 7125-37, 2016 08 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27455395
6.
(+)-Dinapsoline: an efficient synthesis and pharmacological profile of a novel dopamine agonist.
J Med Chem
; 45(17): 3660-8, 2002 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-12166939
7.
Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors.
ACS Med Chem Lett
; 5(2): 188-92, 2014 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-24900796
8.
Small molecule antagonists of the CC chemokine receptor 4 (CCR4).
Bioorg Med Chem Lett
; 17(11): 3141-5, 2007 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17395464
9.
Synthesis and SAR exploration of dinapsoline analogues.
Bioorg Med Chem
; 12(4): 715-34, 2004 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-14759732