Detalhe da pesquisa
1.
Chimeric antigen receptors enable superior control of HIV replication by rapidly killing infected cells.
PLoS Pathog
; 19(12): e1011853, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38100526
2.
Accelerating the development of genetically engineered cellular therapies: a framework for extrapolating data across related products.
Cytotherapy
; 2024 Mar 16.
Artigo
Inglês
| MEDLINE | ID: mdl-38583170
3.
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells.
Mol Ther
; 31(8): 2309-2325, 2023 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37312454
4.
Autologous CD4 T Lymphocytes Modified with a Tat-Dependent, Virus-Specific Endoribonuclease Gene in HIV-Infected Individuals.
Mol Ther
; 29(2): 626-635, 2021 02 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33186691
5.
Challenges and Opportunities of Using Adoptive T-Cell Therapy as Part of an HIV Cure Strategy.
J Infect Dis
; 223(12 Suppl 2): 38-45, 2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33586770
6.
Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology Patients.
Mol Ther
; 26(1): 269-279, 2018 01 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29203150
7.
Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection.
J Immunol
; 189(8): 3815-21, 2012 Oct 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22988032
8.
Long-term stability of clinical-grade lentiviral vectors for cell therapy.
Mol Ther Methods Clin Dev
; 32(1): 101186, 2024 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38282894
9.
Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results.
Nat Med
; 30(5): 1320-1329, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38480922
10.
Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5.
Blood
; 118(4): 1015-9, 2011 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21068438
11.
Tissue-resident memory CAR T cells with stem-like characteristics display enhanced efficacy against solid and liquid tumors.
Cell Rep Med
; 4(6): 101053, 2023 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37224816
12.
BLIMP1 and NR4A3 transcription factors reciprocally regulate antitumor CAR T cell stemness and exhaustion.
Sci Transl Med
; 14(670): eabn7336, 2022 11 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36350986
13.
The Toll-like receptor 1/2 agonists Pam(3) CSK(4) and human ß-defensin-3 differentially induce interleukin-10 and nuclear factor-κB signalling patterns in human monocytes.
Immunology
; 134(2): 151-60, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21896010
14.
BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia.
J Clin Invest
; 131(16)2021 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34396987
15.
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication.
J Clin Invest
; 131(7)2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33571163
16.
Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.
Proc Natl Acad Sci U S A
; 104(47): 18631-5, 2007 Nov 20.
Artigo
Inglês
| MEDLINE | ID: mdl-18006661
17.
Clinical practice: chimeric antigen receptor (CAR) T cells: a major breakthrough in the battle against cancer.
Clin Exp Med
; 20(4): 469-480, 2020 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-32333215
18.
CRISPR-engineered T cells in patients with refractory cancer.
Science
; 367(6481)2020 02 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32029687
19.
CRISPR/Cas9-based genome editing in the era of CAR T cell immunotherapy.
Hum Vaccin Immunother
; 15(5): 1126-1132, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30735463
20.
CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV replication.
J Clin Invest
; 134(9)2024 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38690741