Propofol-induced acute pancreatitis.

WHAT IS KNOWN AND OBJECTIVE: Drug-induced acute pancreatitis comprises only 0.5%-2% of all cases of acute pancreatitis. Propofol is a potentially dangerous drug that can cause acute pancreatitis, but this complication is extremely rare. CASE SUMMARY: A 57-year-old patient developed acute pancreatitis after a planned thyroidectomy. As the common causes of acute pancreatitis were excluded, we believe that the pancreatitis was drug-induced, in this case by a single dose of propofol administered to the patient during the surgery. WHAT IS NEW AND CONCLUSION: We present a rare case of propofol-induced acute necrotising pancreatitis, which is to the best of our knowledge the first fatal case reported in an adult patient.

[Surgical treatment of thyreopathies. Retrospective assessment of the authors' study group]. / Chirurgická lécba tyreopatií. Retrospektivní rozbor vlastní sestavy.

The aim of this study is to expose the change in the access to thyroid gland operations during last 10-15 years when increasing radicality of the operations means any more specific complications in condition of routine detection and visualisation of recurrent laryngeal nerve and sparing of parathyroid glands. Authors analyse 458 patients with thyroid gland disease operated during years 2000-2004. Overall incidence of temporary and permanent paresis of recurrent laryngeal nerve was 2.5% and 1.5% respectively (nerves at risk). There was no permanent bilateral paresis in this study. Persistent hypoparathyroidism occurred after 0.2% of all the operations, and temporary hypoparathyroidism was noted in 10.7%. Results prove that even with increased radicality of performed operations the number of complications is in accordance with values quoted in world literature.

[Blunt injury of abdomen as a part of polytrauma.]. / Tupá poranení bricha v rámci polytraumatu.

In the period from 1 July till 31 August 1998 Central Military Hospital Praha treated 28 multiply injured patients (with polytrauma including blunt injury of abdomen, of which 27 were operated on and 1 patient was treated conservatively. The mean injury severity score was 39.3. CT was used for diagnosis in 21 patients and its total accuracy in the group of patients was 83%. Liver and spleen were injured in 70 % of cases. Of other regions it was the chest (89% of cases) and head (75% of cases) which were most frequently injured. The most imortant for the prognosis of a patient in our group is the injury of head. A successful initial procedure in multiply injured patients (with polytrauma) with a blunt injury of abdomen has to include an intensive antishock treatment, a quick diagnosis and urgent operation, if need be.