Detalhe da pesquisa
1.
Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2.
Mol Psychiatry
; 26(8): 4066-4084, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33235333
2.
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Neurobiol Dis
; 111: 59-69, 2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29197621
3.
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance.
Hum Mol Genet
; 23(1): 104-16, 2014 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23962722
4.
Specific HDAC6 inhibition by ACY-738 reduces SLE pathogenesis in NZB/W mice.
Clin Immunol
; 162: 58-73, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26604012
5.
Antibody humanization by redesign of complementarity-determining region residues proximate to the acceptor framework.
Methods
; 65(1): 68-76, 2014 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23816785
6.
Influence of canonical structure determining residues on antibody affinity and stability.
J Struct Biol
; 185(2): 223-7, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23994046
7.
Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma.
Blood
; 119(11): 2579-89, 2012 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22262760
8.
HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease.
Front Mol Neurosci
; 16: 1231659, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37588057
9.
A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy.
Pain Rep
; 8(6): e1114, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37899940
10.
Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury.
Nat Neurosci
; 26(7): 1229-1244, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37291337
11.
HDAC6-selective inhibitors decrease nerve-injury and inflammation-associated mechanical hypersensitivity in mice.
Psychopharmacology (Berl)
; 237(7): 2139-2149, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-32388618
12.
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model.
Acta Neuropathol Commun
; 7(1): 107, 2019 07 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31277703
13.
Selective Histone Deacetylase 6 Inhibition Normalizes B Cell Activation and Germinal Center Formation in a Model of Systemic Lupus Erythematosus.
Front Immunol
; 10: 2512, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31708928
14.
Author Correction: Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury.
Nat Neurosci
; 27(2): 384, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38253639
15.
Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment.
Acta Neuropathol Commun
; 6(1): 103, 2018 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30270813
16.
Trial designs for chemotherapy-induced peripheral neuropathy prevention: ACTTION recommendations.
Neurology
; 91(9): 403-413, 2018 08 28.
Artigo
Inglês
| MEDLINE | ID: mdl-30054438
17.
Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.
J Clin Invest
; 112(4): 575-87, 2003 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-12925698
18.
Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease.
Neurotherapeutics
; 14(2): 417-428, 2017 04.
Artigo
Inglês
| MEDLINE | ID: mdl-27957719
19.
HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy.
Pain
; 158(6): 1126-1137, 2017 06.
Artigo
Inglês
| MEDLINE | ID: mdl-28267067
20.
Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.
PLoS One
; 12(1): e0169128, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-28060870