Detalhe da pesquisa
1.
Antisense Oligonucleotide Therapy Decreases IL-1ß Expression and Prolongs Survival in Mutant Nlrp3 Mice.
J Immunol
; 211(2): 287-294, 2023 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37256266
2.
ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy.
J Lipid Res
; 63(7): 100237, 2022 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35667416
3.
CHOP-ASO Ameliorates Glomerular and Tubular Damage on Top of ACE Inhibition in Diabetic Kidney Disease.
J Am Soc Nephrol
; 32(12): 3066-3079, 2021 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34479965
4.
A highly efficient modality to block the degradation of tryptophan for cancer immunotherapy: locked nucleic acid-modified antisense oligonucleotides to inhibit human indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase expression.
Cancer Immunol Immunother
; 69(1): 57-67, 2020 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-31802183
5.
Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity.
J Immunother Cancer
; 11(5)2023 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37208130
6.
Identification of Paired-related Homeobox Protein 1 as a key mesenchymal transcription factor in pulmonary fibrosis.
Elife
; 122023 Jun 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37261432
7.
Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer.
Cancer Sci
; 102(6): 1193-200, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21366804
8.
Investigation of the Activity of Antisense Oligonucleotides Targeting Multiple Genes by RNA-Sequencing.
Nucleic Acid Ther
; 31(6): 427-435, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34251864
9.
Using RNA-seq to Assess Off-Target Effects of Antisense Oligonucleotides in Human Cell Lines.
Mol Diagn Ther
; 25(1): 77-85, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33314011
10.
Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.
Cancer Res
; 81(4): 1014-1025, 2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33239430
11.
Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation.
Mol Ther Nucleic Acids
; 21: 656-669, 2020 Sep 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32739778
12.
Anti-Niemann Pick C1 Single-Stranded Oligonucleotides with Locked Nucleic Acids Potently Reduce Ebola Virus Infection In Vitro.
Mol Ther Nucleic Acids
; 16: 686-697, 2019 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31125846
13.
Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity.
J Immunother Cancer
; 7(1): 67, 2019 03 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30871609
14.
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nat Commun
; 10(1): 1280, 2019 03 20.
Artigo
Inglês
| MEDLINE | ID: mdl-30894532
15.
Publisher Correction: ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nat Commun
; 10(1): 3680, 2019 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31417079
16.
Design and Selection of Antisense Oligonucleotides Targeting Transforming Growth Factor Beta (TGF-ß) Isoform mRNAs for the Treatment of Solid Tumors.
Methods Mol Biol
; 1317: 137-51, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26072406
17.
TGF-ß isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity.
Oncotarget
; 6(29): 26770-81, 2015 Sep 29.
Artigo
Inglês
| MEDLINE | ID: mdl-26450853
18.
The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-ß2.
Curr Pharm Biotechnol
; 12(12): 2203-13, 2011 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-21619536
19.
Insulin receptor substrates 1 and 2 but not Shc can activate the insulin receptor independent of insulin and induce proliferation in CHO-IR cells.
Exp Cell Res
; 313(4): 805-15, 2007 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17222824