Detalhe da pesquisa
1.
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
J Antimicrob Chemother
; 79(1): 172-178, 2024 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37995258
2.
Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches.
J Biol Chem
; 295(22): 7595-7607, 2020 05 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32303637
3.
A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism.
Int J Mol Sci
; 22(21)2021 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34768811
4.
Photocobilins integrate B12 and bilin photochemistry for enzyme control.
Nat Commun
; 15(1): 2740, 2024 Mar 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38548733
5.
Redox driven B12-ligand switch drives CarH photoresponse.
Nat Commun
; 14(1): 5082, 2023 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-37604813
6.
Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis.
ACS Infect Dis
; 9(2): 221-238, 2023 02 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36606559
7.
Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors.
Comput Biol Med
; 142: 105245, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35077937
8.
Interaction of the new inhibitor paxlovid (PF-07321332) and ivermectin with the monomer of the main protease SARS-CoV-2: A volumetric study based on molecular dynamics, elastic networks, classical thermodynamics and SPT.
Comput Biol Chem
; 99: 107692, 2022 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-35640480
9.
Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays.
bioRxiv
; 2022 Mar 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35262084
10.
Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2.
Int J Antimicrob Agents
; 59(3): 106542, 2022 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-35093538
11.
Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.
Sci Rep
; 9(1): 1577, 2019 02 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30733479
12.
Characterization of Cytochrome P450 Enzymes and Their Applications in Synthetic Biology.
Methods Enzymol
; 608: 189-261, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30173763