Detalhe da pesquisa
1.
Pharmacological perturbation of thiamine metabolism sensitizes Pseudomonas aeruginosa to multiple antibacterial agents.
Cell Chem Biol
; 29(8): 1317-1324.e5, 2022 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35901793
2.
High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors.
PLoS Pathog
; 5(10): e1000645, 2009 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-19876393
3.
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.
Nat Med
; 19(9): 1157-60, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23913123
4.
Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors.
J Med Chem
; 55(1): 68-83, 2012 Jan 12.
Artigo
Inglês
| MEDLINE | ID: mdl-22098589
5.
Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors.
J Med Chem
; 54(8): 2994-3010, 2011 Apr 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21417236
6.
High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery.
Future Med Chem
; 2(8): 1283-93, 2010 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21426019
7.
Confocal-based method for quantification of diffusion kinetics in microwell plates and its application for identifying a rapid mixing method for high-content/throughput screening.
J Biomol Screen
; 15(2): 138-47, 2010 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-20086214
8.
Functional expression of recombinant tumstatin in stably transformed Drosophila melanogaster S2 cells.
Biotechnol Lett
; 25(3): 185-9, 2003 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-12882569
9.
Improved production of recombinant tumstatin in stably transformed Trichoplusia ni BTI Tn 5B1-4 cells.
Protein Expr Purif
; 35(1): 69-75, 2004 May.
Artigo
Inglês
| MEDLINE | ID: mdl-15039068