Detalhe da pesquisa
1.
Combined translational pharmacometrics approach to support the design and conduct of the first-in-human study of DWP16001.
Br J Clin Pharmacol
; 90(1): 286-298, 2024 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37602795
2.
Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans.
Pharmaceutics
; 15(3)2023 Mar 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36986803
3.
SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction.
Sci Rep
; 13(1): 6256, 2023 04 17.
Artigo
Inglês
| MEDLINE | ID: mdl-37069192
4.
In vitro metabolism of corydaline in human liver microsomes and hepatocytes using liquid chromatography-ion trap mass spectrometry.
J Sep Sci
; 35(9): 1102-9, 2012 May.
Artigo
Inglês
| MEDLINE | ID: mdl-22689485
5.
Effect of a New Prokinetic Agent DA-9701 Formulated with Corydalis Tuber and Pharbitidis Semen on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
Evid Based Complement Alternat Med
; 2012: 650718, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22548118
6.
Hydrophilic interaction chromatography-electrospray ionization tandem mass spectrometric analysis of anastrozole in human plasma and its application to a pharmacokinetic study.
Biomed Chromatogr
; 26(2): 261-6, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21656533
7.
Effect of efavirenz on UDP-glucuronosyltransferase 1A1, 1A4, 1A6, and 1A9 activities in human liver microsomes.
Molecules
; 17(1): 851-60, 2012 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-22252501
8.
In vitro and in vivo metabolism of verproside in rats.
Molecules
; 17(10): 11990-2002, 2012 Oct 12.
Artigo
Inglês
| MEDLINE | ID: mdl-23085650
9.
Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice and Rats.
Pharmaceutics
; 14(6)2022 Jun 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35745783
10.
In vitro metabolism of magnolin and characterization of cytochrome P450 enzymes responsible for its metabolism in human liver microsomes.
Xenobiotica
; 41(5): 358-71, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21294626
11.
Liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry for the simultaneous determination of dimethoxyaschantin, dimethylliroresinol, dimethylpinoresinol, epimagnolin A, fargesin and magnolin in rat plasma.
Biomed Chromatogr
; 25(8): 879-89, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21058411
12.
Corydaline inhibits multiple cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes.
Molecules
; 16(8): 6591-602, 2011 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21826053
13.
Quantification of lamivudine in human plasma by hydrophilic interaction chromatography-tandem mass spectrometry.
J Sep Sci
; 33(6-7): 948-54, 2010 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-20155744
14.
Effects of eupatilin and jaceosidin on cytochrome p450 enzyme activities in human liver microsomes.
Molecules
; 15(9): 6466-75, 2010 Sep 16.
Artigo
Inglês
| MEDLINE | ID: mdl-20877236
15.
Comparative Pharmacokinetics and Pharmacodynamics of a Novel Sodium-Glucose Cotransporter 2 Inhibitor, DWP16001, with Dapagliflozin and Ipragliflozin.
Pharmaceutics
; 12(3)2020 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32183468
16.
In Vitro Metabolism of DWP16001, a Novel Sodium-Glucose Cotransporter 2 Inhibitor, in Human and Animal Hepatocytes.
Pharmaceutics
; 12(9)2020 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32932946
17.
Hydrophilic interaction chromatography-tandem mass spectrometric analysis of irbesartan in human plasma: application to pharmacokinetic study of irbesartan.
J Sep Sci
; 32(14): 2353-8, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19536783
18.
Liquid chromatography-tandem mass spectrometry method of loxoprofen in human plasma.
Biomed Chromatogr
; 23(7): 714-8, 2009 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19296517
19.
Interspecies scaling of oleanolic acid in mice, rats, rabbits and dogs and prediction of human pharmacokinetics.
Arch Pharm Res
; 32(2): 251-7, 2009 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-19280156
20.
Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.
J Sep Sci
; 31(9): 1628-33, 2008 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18401863