[Colpocytology and pregnancy]. / Colpocitología y gestación.

The relationship between cervical infection, cervical intraepithelial neoplasia (CIN), cervical cancer risk factors and pregnancy was studied in a group of 460 pregnant women at the time of their first prenatal examination, each woman was examined by Papanicolaou smear collected with cervexbrush. A total of 301 women (65.4%) with diagnosis of cervical infection was recorded, 4 cases of human papilomavirus infection and two women with CIN I and CIN II. 40 patients were identified with significant risk factors for the development of CIN. CIN prevalence knowledge and pregnancy cervical infection should be considered to prevent the neonates, male partner and women potential risk for cervix invasive carcinoma.

[Tumor of the ovarian juvenile granulose cells. Presentation of a case with an immunohistochemical and ultrastructural study]. / Tumor de células de la granulosa juvenil del ovario. Presentación de un caso con estudio inmunohistoquímico y ultraestructural.

Female, 5 years old; first pregnancy of term, eutocic, weight 3,100 g; breast fed, complete vaccination program. A bronchial pathology that was present seven months later, yielded with medical treatment. Her illness started on September, 1984 after sever trauma by horse kick, presenting with a tumor in left illiac fossa; there was pain, improved by analgesics; the tumor continued to grow up to 5 x 6 cm in diameter, painful on palpation, causing hospital admission. Thirty days later an ultrasonographic study reported an ovoid echogenic and echolucid mass of 6.5 cm in left ovary; an infra-umbilical laparotomy was performed, finding a left ovarian tumarration, ovoid, pink white, with vascular areas, 24 x 18 x 15 cm at maximal diameters, solid, smooth and bright; at section there was gray-white, nodular tissue, with cystic cavities, 0.5 cm. Electronic microscopy an immunochemistry study were carried out in order to confirm the diagnosis of juvenile granulosa cell tumor. The patient died seven months later.

[Ovarian cancer. An anatomicopathological study]. / Cáncer ovárico. Estudio anatomoclínico.

We studied 118 patients with primary ovarian cancer at the Civil Hospital of Guadalajara over a ten-years period; to evaluate incidence, risk factors, clinical aspects, pathology and treatment. Twenty per cent of the patients were classified as stage I, 14 cases (11.8%) stage II, 37 (31%) were stage III and 43 (36%), stage IV. First-stage disease was confirmed by laparotomy; average age was fifty years old, commonly found in patients with invasive carcinoma. Seventy-seven patients received postoperative chemotherapy with cisplatin plus adriamycin and ciclophosphamide or vincrystin, and twelve radiotherapy. Thirteen were evaluated by second look laparotomy, 12 of whom were without clinical residual disease; in 6 we found macroscopic residual tumor. Follow-up was done in 89 patients, and there wasn't clinic disease through 12 to 48 months, with 21 months average. The clinicopathologic study showed predominance of serous and cystic surface epithelium tumours. The aspects of the gross anatomy of the malignant tumours are important from the viewpoint of the benign tumours differentiation.