Detalhe da pesquisa
1.
Leveraging single-cell RNA sequencing to unravel the impact of aging on stroke recovery mechanisms in mice.
Proc Natl Acad Sci U S A
; 120(25): e2300012120, 2023 06 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37307473
2.
Efficacy, safety, and survival findings after long-term follow-up of ZGJAK002: A phase 2 study comparing jaktinib at 100 mg twice daily (BID) and 200 mg once daily (QD) in patients with myelofibrosis.
Am J Hematol
; 99(4): 774-779, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38343062
3.
Network pharmacology analysis and experimental verification of the antitumor effect and molecular mechanism of isocryptomerin on HepG2 cells.
Drug Dev Res
; 85(2): e22165, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38400652
4.
Efficacy and safety of the B-domain-deleted TQG202 for on-demand treatment in moderate and severe haemophilia A patients: A multicentre, single-arm trial.
Haemophilia
; 29(4): 997-1004, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-36913439
5.
Women and girls with haemophilia: A retrospective cohort study in China.
Haemophilia
; 29(2): 578-590, 2023 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-36595620
6.
Factor IX inhibitors in haemophilia B: A report of National Haemophilia Registry in China.
Haemophilia
; 29(1): 123-134, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36163649
7.
Cyanidin-3-O-Glucoside Induces the Apoptosis of Human Gastric Cancer MKN-45 Cells through ROS-Mediated Signaling Pathways.
Molecules
; 28(2)2023 Jan 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36677726
8.
Efficacy, safety and bioequivalence of the human-derived B-domain-deleted recombinant factor VIII TQG202 for prophylaxis in severe haemophilia A patients.
Haemophilia
; 28(6): e219-e227, 2022 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-35996199
9.
Safety and efficacy of jaktinib in the treatment of Janus kinase inhibitor-naïve patients with myelofibrosis: Results of a phase II trial.
Am J Hematol
; 97(12): 1510-1519, 2022 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36054786
10.
Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches.
Immun Ageing
; 19(1): 34, 2022 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35879802
11.
PARP-1 inhibitors enhance the chemosensitivity of leukemia cells by attenuating NF-кB pathway activity and DNA damage response induced by Idarubicin
Acta Biochim Biophys Sin (Shanghai)
; 54(1): 91-98, 2022 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-35130631
12.
2-(Naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via ROS-mediated MAPK, AKT, and STAT3 signaling pathways in HepG2 human hepatocellular carcinoma cells.
Drug Chem Toxicol
; 45(1): 33-43, 2022 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-35100937
13.
Peimine-induced apoptosis and inhibition of migration by regulating reactive oxygen species-mediated MAPK/STAT3/NF-κB and Wnt/ß-catenin signaling pathways in gastric cancer MKN-45 cells.
Drug Dev Res
; 83(7): 1683-1696, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36048972
14.
Effects of Residual Composition and Distribution on the Structural Characteristics of the Protein.
Int J Mol Sci
; 23(22)2022 Nov 17.
Artigo
Inglês
| MEDLINE | ID: mdl-36430742
15.
Atractylodin Induces Apoptosis and Inhibits the Migration of A549 Lung Cancer Cells by Regulating ROS-Mediated Signaling Pathways.
Molecules
; 27(9)2022 May 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35566297
16.
Matrix metalloprotein-triggered, cell penetrating peptide-modified star-shaped nanoparticles for tumor targeting and cancer therapy.
J Nanobiotechnology
; 18(1): 48, 2020 Mar 17.
Artigo
Inglês
| MEDLINE | ID: mdl-32183823
17.
The design of 1,4-naphthoquinone derivatives and mechanisms underlying apoptosis induction through ROS-dependent MAPK/Akt/STAT3 pathways in human lung cancer cells.
Bioorg Med Chem
; 27(8): 1577-1587, 2019 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30846406
18.
Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents.
J Enzyme Inhib Med Chem
; 34(1): 1210-1217, 2019 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31286781
19.
Glycitein induces reactive oxygen species-dependent apoptosis and G0/G1 cell cycle arrest through the MAPK/STAT3/NF-κB pathway in human gastric cancer cells.
Drug Dev Res
; 80(5): 573-584, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30916421
20.
Quinalizarin induces cycle arrest and apoptosis via reactive oxygen species-mediated signaling pathways in human melanoma A375 cells.
Drug Dev Res
; 80(8): 1040-1050, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31432559