[Effect of vitamin B6 status on selenium retention in the tissues in rats fed selenium from sodium selenate].

OBJECTIVE: To study the effect of vitamin B6 status on selenium retention in tissues. METHODS: Weaning male Wistar, 4-week-old, fed with vitamin B6-selenium-deficient basal diet for 3 weeks was randomly divided into 6 groups. There were six experimental diets, that is basal diet (vitamin B6-selenium-deficient), basal diet supplemented with vitamin B6, and supplemented with Se 0.25 mg/kg as Na2 SeO4 and vitamin B6 0, 1.0 2.5 and 5.0 mg/kg diet as pyridoxine HCl for 4 weeks, three-days metabolic test was carried out before finished the study. RESULTS: Compared with each group supplemented with vitamin B6, the vitamin B6 deficient groups had a significantly low body weight gain and diet availability, and lower selenium retention in heart, liver, and kidneys, however, the status of vitamin B6 had no significant effect on the weight and selenium retention in the testes. Vitamin B6 had no significant influence on the selenium apparent absorption and retention by the three days metabolic test. CONCLUSION: Providing adequate vitamin B6 could be benefit for improving rat growth and development and increasing selenium retention in the tissues.

[Observation on the efficacy of glycine chelated iron (II) in improving nutritional anemia in children].

OBJECTIVE: To observe the efficiency of glycine chelated iron (II) on nutritional iron-deficient anemia. METHOD: The iron-deficient anemic children (120 subjects), aged 7 - 12 were randomly divided into two groups, one group as a control group given with a placeboes and another group treated with glycine chelated iron (II) for one month. RESULTS: Compared with the control group, the addition of glycine chelated iron (II) group had a significantly higher hemoglobin level ( > 10 g/L) in whole blood and a lower free erythrocyte protoporphyrin (FEP) content. CONCLUSION: The iron from glycine chelated iron (II) have a role in improving nutritional iron-deficient anemia in children.

[Evaluation on glycine chelated iron (II) in improving nutritional anemia in rats].

OBJECTIVE: In order to evaluate the efficacy of glycine chelated iron (II) in improving nutritional anemia in rats. METHODS: After weaning wistar rats, weighing 50 - 60g, were fed the iron deficient diet for three weeks, whole blood was taken from rat's tail to measure Hb, then the rats were randomly divided into five groups by Hb, that is the control group fed with iron deficient diet, three groups fed the diets supplemented with different glycine chelated iron (II), and another group fed with the diet added with lactate iron. Each group was fed respective diets for four weeks and indicators related to iron-deficient nutritional anemia were evaluated. RESULTS: The addition of glycine chelated iron (II) did improve the growth and development of rats, increase the hemoglobin level and the iron retention in spleen, decrease free erythrocyte protoporphyrin (FEP) content in whole blood, and there was no significant difference between three supplemental groups with glycine chelated iron (II) and the group with lactate iron. CONCLUSION: glycine chelated iron (II) can be used as a reasonable iron supplement in improving iron-deficient nutritional anemia.