[Clinical biological behavior and treatment strategy of hemangioma in oral and maxillofacial region].

Hemangioma can not be prevented until nowadays. Early identification and definite diagnosis are necessary to achieve the best outcome. The clinical biological behaviors of hemangiomas in oral and maxillofacial region are completely investigated and deeply analyzed in this paper. There are two distinct phrase of rapid proliferation of hemangioma, with explicit onset and lasting time. Although there is still controversy over the treatment modality of hemangiomas in oral and maxillofacial region, the only way to success is to treat the lesions in early stage, in particular, the first rapid proliferation phrase is the best opportunity and strategic point to control the growth of hemangioma or even cure the disease. Upon definite diagnosis, laser therapy, sclerotherapy and oral steroids are among the treatment options. The protocol of laser therapy and sclerotherapy is addressed in this paper. Careful planning and appropriate manipulation are the key components to the management of hemangioma in oral and maxillofacial region.

[Research on histologic changes of periodontal tissue, testification of TNF-alpha and their relationship in diabetics rats].

OBJECTIVE: The histologic and TNF-alpha changes of the experimental periodontitis were studied in diabetic rat model in different periods. The mechanism of the occurring and developing of periodontitis was probed on the aspect of cytology. METHODS: The diabetic rat models were established by injecting streptozotocin into its abdomen. The local stimulation was caused by tiring silk thread to teeth. The histologic changes of periodontium were observed at 6,9,and 12 weeks. The level of TNF-alpha was testified using immunohistochemistry method at 12 weeks. RESULTS: Periodontitis occurred in diabetic rats earlier than in non-diabetic ones. The destructions were more severe and more widely in diabetic rats than in non-diabetic ones. The level of TNF-alpha was higher in the experimental periodontium of diabetic rats than those non-diabetics. CONCLUSIONS: Diabetes mellitus has an accelerating effect on occurring and developing of periodontitis. When with diabetes, more cytokines were released, and cause the unbalance of ruin and repair and result in the enhancing of periodontitis.